Results 131 to 140 of about 2,498,124 (314)

Using high-density exon arrays to profile gene expression in closely related species [PDF]

, 2009
Lan Lin, Song Liu, Heather Brockway, Junhee Seok, Peng Jiang, Wing Hung Wong, Yi Xing   +6 more
openalex   +1 more source

High-throughput single-cell gene-expression profiling with multiplexed error-robust fluorescence in situ hybridization

Proceedings of the National Academy of Sciences of the United States of America, 2016
J. Moffitt, Junjie Hao, Guiping Wang, Kok Hao Chen, H. Babcock, X. Zhuang   +5 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Gene expression profiling of Healthy Centenarians

The Scientific World Journal, 2001
M. Venanzoni, C. Franceschi, S. Sorbi, L. Storari, S. Giunta, A. Seth   +5 more
doaj   +1 more source

Gene Expression Profiling Defines ATP as a Key Regulator of Human Dendritic Cell Functions [PDF]

, 2007
Nathalie Bles, Michael Horckmans, Anne Lefort, F. Libert, Pascale Macours, Hakim El Housni, Frédéric Marteau, Jean‐Marie Boeynaems, Didier Communi   +8 more
openalex   +1 more source

Gene Expression Profiling of Early Acute Febrile Stage of Dengue Infection and Its Comparative Analysis With Streptococcus pneumoniae Infection [PDF]

, 2021
Leena H. Bajrai, Sayed Sartaj Sohrab, Thamir A. Alandijany, Mohammad Mobashir, Muddassir Reyaz, Mohammad Amjad Kamal, Ahmad Firoz, Shabana Parveen, Esam I. Azhar   +8 more
openalex   +1 more source

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling.

Cancer Cell, 2002
E. Yeoh, M. Ross, S. Shurtleff, W. Williams, D. Patel, R. Mahfouz, F. Behm, S. Raimondi, M. Relling, Anami R. Patel, Cheng Cheng, D. Campana, D. Wilkins, Xiaodong Zhou, Jinyan Li, Huiqing Liu, C. Pui, W. Evans, C. Naeve, L. Wong, J. Downing   +20 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Gene expression profiles in human gastric cancer: expression of maspin correlates with lymph node metastasis [PDF]

, 2005
Masanori Terashima, Chihaya Maesawa, Keisuke Oyama, S. Ohtani, Yuji Akiyama, Satoshi Ogasawara, Akinori Takagane, Kazuyoshi Saito, Takahiro Masuda, Norio Kanzaki, S Matsuyama, Yutaka Hoshino, M Kogure, Mari Gotoh, Masatoshi Shirane, Koichiro Mori   +15 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source