Results 191 to 200 of about 2,789,846 (387)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

cDNA cloning, expression profile, and genomic structure of human and mouse RNF10/Rnf 10 genes, encoding a novel RING finger protein [PDF]

, 2000
Naohiko Seki, Atsushi Hattori, Sumio Sugano, Masami Muramatsu, Takashi Saito   +4 more
openalex   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Differential Pituitary Gene Expression Profiles Associated- To Aging and Spontaneous Tumors as Revealed by cDNA Expression Array [PDF]

, 2000
D. Goidin
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Gene-Expression Profiles in Hereditary Breast Cancer [PDF]

, 2001
Ingrid Hedenfalk, David Duggan, Y Chen, Michael D. Radmacher, Michael Bittner, Richard H. Simon, Paul S. Meltzer, B.A. Gusterson, Manel Esteller, Olli Kallioniemi, Benjamin S. Wilfond, Alexander Borg, Jeffrey M. Trent, Mark Raffeld, Zohar Yakhini, Amir Ben‐Dor, E.R. Dougherty, Juha Kononen, Lukas Bubendorf, Wilfrid Fehrle, Stefania Pittaluga, Sofia Gruvberger, Niklas Loman, Oskar T. Johannsson, Håkan Olsson, Guido Sauter   +25 more
openalex   +3 more sources

T cell gene expression profiles [PDF]

, 2000
G. M. Wilson
openalex   +1 more source

Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues

Nature Protocols, 2015
Je H. Lee, Evan R. Daugharthy, J. Scheiman, Reza Kalhor, Thomas C. Ferrante, Richard Terry, B. Turczyk, Joyce L. Yang, Ho Suk Lee, John D Aach, Kun Zhang, G. Church   +11 more
semanticscholar   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Gene expression profiling and pathway analysis in acute myeloid leukaemia-normal karyotype patients. [PDF]

PLoS One
Ambayya A, Razali R, Sulong S, Yap YY, Selvaratnam V, Sathar J, Hassan R.   +6 more
europepmc   +1 more source