Results 181 to 190 of about 4,727,278 (305)

Integrating Metabolic and Gene Expression Profiling of Glucosinolate Biosynthesis Under Drought Stress in <i>Brassica oleracea</i>. [PDF]

Int J Mol Sci
Ben Ammar H, Kabtni S, Arena D, Amari M, Al Achkar N, Branca F, Marghali S.   +6 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Antibacterial and Antibiofilm Potential of Thymol-Benzimidazolium-Chalcone Hybrids Against Clinical MRSA Strains: Insights from Gene Expression Profiling and Molecular Docking. [PDF]

Antibiotics (Basel)
Yakut S, Ünver H, Yiğin A, Çimentepe M, Yıldız Zeyrek F, Öztürk Çimentepe Ö, Yildirim M.   +6 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Comprehensive Investigation of a Novel Schiff Base: Synthesis, Anticancer Efficacy, Gene Expression Profiling, and Computational Analyses. [PDF]

Pharmaceuticals (Basel)
Agbektas T, Pazarcı Ö, Tas A, Huseynzada A, Guliyev R, Hasanova U, Buluz EC, Kaya S, Morales-Bayuelo A, Silig Y.   +9 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Gene Expression Profiles

Report related to the Massive amount gene expression profiles related to tested food along the food chain - In particular spoilage and safety aspects will be ...
openaire   +1 more source

Hair follicle gene expression profiling in the SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS). [PDF]

BMC Med Genomics
Buschur KL, Martorella M, Garcia-Flores R, Smith BM, Ziosi M, Barjaktarevic I, Bleecker ER, Christenson SA, Comellas AP, Criner GJ, Dransfield MT, Hansel NN, Kaner RJ, Krishnan JA, Meyers DA, Oelsner EC, Ortega VE, Paine R, Woodruff PG, Barr RG, Lappalainen T.   +20 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Gene Expression Profiling and Prognostic Significance of Nuclear and Membrane Progesterone Receptors in Head and Neck Squamous Cell Carcinoma. [PDF]

Int J Mol Sci
Jelačić J, Milutin N, Stojković I, Vugrinec O, Kvolik Pavić A, Vušković S, Mumlek I, Zubčić V, Leović D, Bilić M, Ozretić P.   +10 more
europepmc   +1 more source