Results 161 to 170 of about 4,727,278 (305)

Gene Expression Profiling of Adipose Tissue in Enshi Black Pigs Subjected to Cold Stress. [PDF]

Vet Sci
Zhang T, Wang L, Yang S, Hu G, Zhang D.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Expanding the Gene Expression Profiling of Drug Transporters and Drug-Metabolizing Enzymes to Include the Upper Female Reproductive Tract. [PDF]

Pharmaceutics
Le A, Valicherla GR, Zhang J, Wang L, Donnelly MK, Bies R, Rohan LC.   +6 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Gene expression profiling identifies potential biomarkers for vaso-occlusive episodes in sickle cell disease. [PDF]

JCI Insight
Bhat V, Yoo JJ, Ponna S, Potdar AA, Patel AP, Yu GK, Gibson G, Sheehan VA.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Profiling viral gene expression in lymphomas

Brazilian Journal of Infectious Diseases
Dirk P. Dittmer
doaj   +1 more source

Stage-specific gene expression profiling of <i>Toxocara canis</i> in canine and human hosts: Implications for the pathogenesis and transmission of zoonotic diseases. [PDF]

Open Vet J
Al Shabbani AHA, Al-Kaeebi SRA, Madhloom MH, Alfatlawi MAA.   +3 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Integrated Metabolomics and Targeted Gene Expression Profiling Reveal the Arginine-Anthocyanin Axis in Pomegranate Aril Paleness Disorder. [PDF]

Curr Issues Mol Biol
Rezaei M, Heidari P, Reim S.
europepmc   +1 more source