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The human genome and gene expression profiling
Journal of Plastic, Reconstructive & Aesthetic Surgery, 2006The mapping and sequencing of the human genome has generated a large resource for answering questions about human disease. This achievement is akin in scientific importance to developing the periodic table of elements. Plastic surgery has always been at the frontier medical research.
Chin, David +4 more
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Gene Expression Profiling of Human Cancers
Annals of the New York Academy of Sciences, 2004Abstract: DNA microarrays allow us to visualize simultaneously the expression of potentially all genes within a cell population or tissue sample—revealing the “transcriptome.” The analysis of this type of data is commonly called “gene expression profiling” (GEP) because it provides a comprehensive picture of the pattern of gene expression in a ...
Giselda, Bucca +5 more
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Gene expression profiles in esophageal adenocarcinoma
The Annals of Thoracic Surgery, 2004The incidence of esophageal adenocarcinoma (EAC) has risen dramatically in the last two decades. As with other malignancies, changes in gene expression play a key role in the development and progression of these tumors.Microarray analysis was used to study gene expression of 12,000 genes in EAC specimens.
Peter S, Dahlberg +5 more
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2010
Gene expression (GE) analyses by use of microarrays (MAs) have become an important part of biomedical and clinical research and the resulting data may provide important information regarding pathogenesis and be extrapolated for use in diagnosing/prognosticating lymphomas and leukemias.
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Gene expression (GE) analyses by use of microarrays (MAs) have become an important part of biomedical and clinical research and the resulting data may provide important information regarding pathogenesis and be extrapolated for use in diagnosing/prognosticating lymphomas and leukemias.
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Gene Expression Profiling of Melanocytic Lesions
The American Journal of Dermatopathology, 2003DNA microarrays, microscopic grids of DNA, can be used to assess gene expression within a particular cell or cell population. Since DNA from thousands of genes can be hybridized and analyzed in one experiment, researchers can globally characterize genes expressed in normal and various pathologic states.
John T, Seykora +4 more
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Profiling Gene Expression in Kidney Development
Nephron Experimental Nephrology, 2004Insights into the normal development of the kidney have been derived from metanephric organ cultures, knockout mice and the later definition of the responsible single genetic abnormalities in some human congenital renal tract malformations. Deciphering of the human genome and the ability to examine multiple messenger RNA has opened new vistas and the ...
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Hematology/Oncology Clinics of North America, 2001
Elizabeth A. Raetz +3 more
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Elizabeth A. Raetz +3 more
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