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Gene expression profiling of porokeratosis
Journal of Cutaneous Pathology, 2008Background: Porokeratosis (PK) represents a heterogeneous group of disorders of keratinization and has a wide variety of clinical manifestations. PK may exhibit similarities with psoriasis at both clinical and molecular levels. The genetic basis and pathogenesis for PK remain elusive.Methods: We studied the transcriptional profiles of three pairwise ...
Zheng-Hua, Zhang +11 more
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Gene Expression Profiling in Ecotoxicology
Ecotoxicology, 2003Gene expression profiling is a powerful new end point for ecotoxicology and a means for bringing the genomics revolution to this field. We review the usefulness of gene expression profiling as an end point in ecotoxicology and describe methods for applying this approach to non-model organisms.
Terry W, Snell +2 more
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Gene Expression Profiling in Rheumatology
2007In the last decade, the analysis of gene expression in tissues and cells has evolved from the analysis of a selected set of genes to an efficient high throughput whole-genome screening approach of potentially all genes expressed. Development of sophisticated methodologies such as microarray technology allows an open-ended survey to identify ...
van der Pouw Kraan, Tineke C. T. M. +5 more
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Expression Profiling of Organellar Genes
2012Due to their endosymbiotic origin, expression of plastid and mitochondrial genes retains several features of prokaryotes. Nevertheless, plant organelles acquired novel specific traits during evolution. Furthermore, due to the migration of many genes to the nucleus of the host cell, complex anterograde and retrograde signalling pathways evolved to ...
Cardi T, Giegé P, Kahlau S, Scotti N
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Gene expression profiling of lymphomas
Current Oncology Reports, 2001The functional phenotype of a cell results from the simultaneous action of many thousands of genes, which until recently could not be assessed using standard molecular biological techniques. Indeed, molecular genetics and cellular biology inadequately explain the molecular physiology of normal and diseased cells and provide a fragmented view of the ...
U, Hegde, W H, Wilson
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Tissue Classification with Gene Expression Profiles
Journal of Computational Biology, 2000Constantly improving gene expression profiling technologies are expected to provide understanding and insight into cancer-related cellular processes. Gene expression data is also expected to significantly aid in the development of efficient cancer diagnosis and classification platforms.
Amir Ben-Dor +5 more
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Gene Expression Profiling in Asthma
2013Transcriptomics (gene expression profiling) refers to the quantitative and qualitative characterization of the collection of ribose nucleic acid (RNA) elements expressed in a biological system and represents one of the first truly genome-wide hypothesis-free investigative approaches in molecular biology.
Joanne, Sordillo, Benjamin A, Raby
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Gene Expression Profiling: Metatranscriptomics
2011Metatranscriptomics has been developed to help understand how communities respond to changes in their environment. Metagenomic studies provided a snapshot of the genetic composition of the community at any given time. However, short-timescale studies investigating the response of communities to rapid environmental changes (e.g.
Jack A, Gilbert, Margaret, Hughes
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Methods to Profile Gene Expression
Trends in Cardiovascular Medicine, 2001Molecular biology has been influenced tremendously by recent technological advancements in miniaturization and automation. One consequence has been the development of robust and sensitive methods to analyze gene expression. The ability to evaluate systematically the expression of every mammalian gene is now technically feasible.
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Gene Expression Profiles in Cutaneous Oncology
Dermatologic Clinics, 2023Skin cancer is highly curable under most circumstances; however, locally advanced or metastatic disease historically has poor outcomes and limited treatment options. Treatment has recently been advanced by the discovery of pertinent genes influencing pathogenesis and further revolutionized by the advent of specific gene expression profiles (GEPs). GEPs
Bo M, Kitrell +6 more
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