Results 21 to 30 of about 753,249 (345)

Partition Decoupling for Multi-gene Analysis of Gene Expression Profiling Data [PDF]

open access: yes, 2011
We present the extention and application of a new unsupervised statistical learning technique--the Partition Decoupling Method--to gene expression data.
Braun, Rosemary   +3 more
core   +5 more sources

Stochastic neural network models for gene regulatory networks [PDF]

open access: yes, 2003
Recent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of genome dynamics by means of mathematical modelling.
Burrage, K., Tian, T.
core   +2 more sources

Using transcriptomics to guide lead optimization in drug discovery projects : lessons learned from the QSTAR project [PDF]

open access: yes, 2015
The pharmaceutical industry is faced with steadily declining R&D efficiency which results in fewer drugs reaching the market despite increased investment.
Bender, Andreas   +10 more
core   +2 more sources

Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus - associated hepatocellular carcinoma. [PDF]

open access: yes, 2014
Background: The molecular mechanisms whereby hepatitis B virus (HBV) induces hepatocellular carcinoma (HCC) remain elusive. We used genomic and molecular techniques to investigate host-virus interactions by studying multiple areas of the same liver from
Becker S   +16 more
core   +1 more source

The MBD7 complex promotes expression of methylated transgenes without significantly altering their methylation status. [PDF]

open access: yes, 2017
DNA methylation is associated with gene silencing in eukaryotic organisms. Although pathways controlling the establishment, maintenance and removal of DNA methylation are known, relatively little is understood about how DNA methylation influences gene ...
Chen, Xuemei   +20 more
core   +3 more sources

Gene expression profiling to study racial differences after heart transplantation. [PDF]

open access: yes, 2015
BackgroundThe basis for increased mortality after heart transplantation in African Americans and other non-Caucasian racial groups is poorly defined. We hypothesized that increased risk of adverse events is driven by biologic factors.
Anderson, Allen S   +12 more
core   +2 more sources

Gene expression profiling: methods and protocols

open access: yesEuropean Journal of Histochemistry, 2012
There must be some good reasons to last for a second edition on the very same topic: likely, the topic is crucial to basic and applied science, it is a very rapid evolving topic and there must occurred some breakthroughs meanwhile the two editions. Well,
Manuela Monti
doaj   +1 more source

Digital gene expression analysis of the zebra finch genome [PDF]

open access: yes, 2010
Background: In order to understand patterns of adaptation and molecular evolution it is important to quantify both variation in gene expression and nucleotide sequence divergence.
Balakrishnan, C.N.   +3 more
core   +4 more sources

Gene Expression Profiling via Multigene Concatemers.

open access: yesPLoS ONE, 2011
We established a novel method, Gene Expression Profiling via Multigene Concatemers (MgC-GEP), to study multigene expression patterns simultaneously.
Kai Jin, Xiaoli Zheng, Yuxian Xia
doaj   +1 more source

Gene Expression Profiling and Outcome Prediction in Non-Hodgkin Lymphoma [PDF]

open access: yes, 2006
Gene expression profiling with microarrays has provided new insights into the molecular biology of tumors can that underlie differences in responses to therapy and patient outcomes. In diffuse large B-cell lymphoma, gene expression profiling has revealed
Dave   +6 more
core   +1 more source

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