Results 21 to 30 of about 2,498,124 (314)

Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance The spatial organization of RNAs within cells and spatial patterning of cells within tissues play crucial roles in many biological processes.
C. Xia   +4 more
semanticscholar   +1 more source

Gene Expression Profiling in Organ Transplantation

open access: yesInternational Journal of Nephrology, 2011
Aim of Review. Huge effort is being made among the transplant community investigating novel biomarkers that enable transplant clinicians to identify patients at risk for allograft rejection or those who will develop tolerance so that immunosuppression ...
Osama Ashry Ahmed Gheith
doaj   +1 more source

Joint profiling of chromatin accessibility and gene expression in thousands of single cells

open access: yesScience, 2018
Single-cell chromatin and RNA analysis Single-cell analyses have begun to provide insight into the differences among and within the individual cells that make up a tissue or organism.
Junyue Cao   +13 more
semanticscholar   +1 more source

Transcriptome analysis of bladder biopsy from interstitial cystitis/bladder pain syndrome patients

open access: yesGenomics Data, 2014
Interstitial cystitis and bladder pain syndrome (IC/BPS) are terms used to describe a heterogeneous chronic pelvic and bladder pain disorder. Despite its significant prevalence, the disease etiology is not well understood and providing diagnosis and ...
Stephen J. Walker   +6 more
doaj   +1 more source

Gene expression profiling to predict responsiveness to immunotherapy

open access: yesCancer Gene Therapy, 2016
Recent clinical successes with immunotherapy have resulted in expanding indications for cancer therapy. To enhance antitumor immune responses, and to better choose specific strategies matched to patient and tumor characteristics, genomic-driven precision
N. Jamieson, A. Maker
semanticscholar   +1 more source

Enhanced Th17 Responses in Patients with Autoimmune Hepatitis

open access: yesMiddle East Journal of Digestive Diseases, 2019
BACKGROUND T cells are major players in chronic inflammatory diseases such as autoimmune hepatitis (AIH). However, it is not clear which subset of T cells participates in the pathophysiology of the disease.
Farinaz Behfarjam   +2 more
doaj   +1 more source

Evaluation of bovine embryo quality based on gene expression profiling using whole-transcriptome amplification

open access: yesThe Journal of Reproduction and Development
This study aimed to develop a method to evaluate the quality of bovine in vitro fertilized (IVF) embryos based on gene expression profiling via whole-transcriptome amplification.
Takashi FUJII   +4 more
doaj   +1 more source

Gene expression profiling of solitary fibrous tumors. [PDF]

open access: yesPLoS ONE, 2013
Solitary fibrous tumors (SFTs) are rare spindle-cell tumors. Their cell-of-origin and molecular basis are poorly known. They raise several clinical problems.
François Bertucci   +10 more
doaj   +1 more source

Comparing Bioinformatic Gene Expression Profiling Methods: Microarray and RNA-Seq

open access: yesMedical science monitor basic research, 2014
Understanding the control of gene expression is critical for our understanding of the relationship between genotype and phenotype. The need for reliable assessment of transcript abundance in biological samples has driven scientists to develop novel ...
K. Mantione   +6 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

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