Results 21 to 30 of about 428,234 (308)

The profiling and analysis of gene expression in human periodontal ligament tissue and fibroblasts

Clinical and Experimental Dental Research, 2022
Objectives The periodontal ligament (PDL) is an important component of periodontium to support dental structure in the alveolar socket. Regeneration of PDL tissue is an effective treatment option for periodontal disease and the profiling of genes ...
Nattakarn Hosiriluck, Haruna Kashio, Ayuko Takada, Itaru Mizuguchi, Toshiya Arakawa   +4 more
doaj   +1 more source

Gene expression profiling of the inner ear [PDF]

Journal of Anatomy, 2015
AbstractThe identification of transcriptional differences has served as an important starting point in understanding the molecular mechanisms behind biological processes and systems. The developmental biology of the inner ear, the biology of hearing and of course the pathology of deafness are all processes that warrant a molecular description if we are
Schimmang, Thomas, Maconochie, Mark
openaire   +3 more sources

Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity

eLife, 2016
Mammalian lifespan differs by >100 fold, but the mechanisms associated with such longevity differences are not understood. Here, we conducted a study on primary skin fibroblasts isolated from 16 species of mammals and maintained under identical cell ...
Siming Ma, Akhil Upneja, Andrzej Galecki, Yi-Miau Tsai, Charles F Burant, Sasha Raskind, Quanwei Zhang, Zhengdong D Zhang, Andrei Seluanov, Vera Gorbunova, Clary B Clish, Richard A Miller, Vadim N Gladyshev   +12 more
doaj   +1 more source

Gene expression profile of sprinter’s muscle [PDF]

The FASEB Journal, 2007
We have characterized the global gene expression profile in left vastus lateralis muscles of sprinters and sedentary men. The gene expression profile was analyzed by using serial analysis of gene expression (SAGE) method. The abundantly expressed transcripts in the sprinter's muscle were mainly involved in contraction and energy metabolism, whereas six
Munehiro Shindo, Jonny St-Amand, Hiroaki Tanaka, Naoko Shono, Mayumi Yoshioka   +4 more
openaire   +3 more sources

Microarray expression technology in clinical research of non-Hodgkin lymphoma [PDF]

Archive of Oncology, 2007
Nowadays, in genomocentric era accelerated research of the human genome coupled with advances is enabling the comprehensive molecular profiling of human tissue.
Baltić Vladimir, Baltić Milan
doaj   +1 more source

Evaluation of bovine embryo quality based on gene expression profiling using whole-transcriptome amplification

The Journal of Reproduction and Development
This study aimed to develop a method to evaluate the quality of bovine in vitro fertilized (IVF) embryos based on gene expression profiling via whole-transcriptome amplification.
Takashi FUJII, Takamasa MUKAI, Shoji HASEGAWA, Toh-ichi HIRATA, Ken SAWAI   +4 more
doaj   +1 more source

Gene Expression Profiling of Gastric Cancer [PDF]

Journal of Proteomics & Bioinformatics, 2011
Gastric cancer is the second leading cause of cancer death worldwide, both in men and women. A genomewide gene expression analysis was carried out to identify differentially expressed genes in gastric adenocarcinoma tissues as compared to adjacent normal tissues.
Marimuthu, A.N., Jacob, H.K., Jakharia, A., Subbannayya, Y., Keerthikumar, S., Kashyap, M.K., Goel, R., Balakrishnan, L., Dwivedi, S., Pathare, S., Dikshit, J.B., Maharudraiah, J., Singh, S., Kumar, G.S., Vijayakumar, M., Veerendra Kumar, K.V., Premalatha, C.S., Tata, P., Hariharan, R., Roa, J.C., Prasad, T.S., Chaerkady, R., Kumar, R.V., Pandey, A.   +23 more
openaire   +3 more sources

Transcriptome analysis of bladder biopsy from interstitial cystitis/bladder pain syndrome patients

Genomics Data, 2014
Interstitial cystitis and bladder pain syndrome (IC/BPS) are terms used to describe a heterogeneous chronic pelvic and bladder pain disorder. Despite its significant prevalence, the disease etiology is not well understood and providing diagnosis and ...
Stephen J. Walker, Marc Colaco, David S. Koslov, Tristan Keys, Robert J. Evans, Gopal H. Badlani, Karl-Erik Andersson   +6 more
doaj   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source