Results 141 to 150 of about 1,086,983 (374)

Gene Expression and Stress Response Mediated by the Epigenetic Regulation of a Transposable Element Small RNA

PLoS Genetics, 2012
The epigenetic activity of transposable elements (TEs) can influence the regulation of genes; though, this regulation is confined to the genes, promoters, and enhancers that neighbor the TE.
Andrea D. McCue, Saivageethi Nuthikattu, S. H. Reeder, R. Slotkin   +3 more
semanticscholar   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

Stress Marker Signatures in Lesion Mimic Single and Double Mutants Identify a Crucial Leaf Age-Dependent Salicylic Acid Related Defense Signal [PDF]

, 2017
Plants are exposed to abiotic and biotic stress conditions throughout their lifespans that activates various defense programs. Programmed cell death (PCD) is an extreme defense strategy the plant uses to manage unfavorable environments as well as during ...
Brosche, Mikael, Kaurilind, Eve
core   +1 more source

Genes Preferring Non-AUG Start Codons in Bacteria [PDF]

arXiv, 2020
Here we investigate translational regulation in bacteria by analyzing the distribution of start codons in fully assembled genomes. We report 36 genes (infC, rpoC, rnpA, etc.) showing a preference for non-AUG start codons in evolutionarily diverse phyla ("non-AUG genes").
arxiv  

Spatial clustering and common regulatory elements correlate with coordinated gene expression [PDF]

, 2019
Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can generate coordinated gene expression.
arxiv   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Molecular characterization of MicroRNA-silenced TNL-1 (MIST1) and its role in plant defense [PDF]

, 2022
miRNAs are sequence-dependent negative regulators of gene expression involved in many relevant plant processes, including immunity. Activation of defence genes can negatively impact plant fitness, and thus needs to be fine-tuned.
Beuzon-Lopez, Carmen del Rosario, Del Espino Pérez, Ángel, López-Márquez, Diego, López-Pagán, Nieves, Rodriguez-Bejarano, Eduardo, Ruiz-Albert, Francisco Javier   +5 more
core  

Global Methylomic and Transcriptomic Analyses Reveal the Broad Participation of DNA Methylation in Daily Gene Expression Regulation of Populus trichocarpa

Frontiers in Plant Science, 2019
Changes in DNA methylation patterns in different tissues, at various developmental stages, and under environmental stimuli have been investigated in plants.
Lixiong Liang, Lixiong Liang, Yingying Chang, Yingying Chang, Junqian Lu, Junqian Lu, Xiaojuan Wu, Xiaojuan Wu, Qi Liu, Qi Liu, Weixi Zhang, Weixi Zhang, Xiaohua Su, Xiaohua Su, Bingyu Zhang, Bingyu Zhang   +15 more
doaj   +1 more source

Epigenetic regulation in plant abiotic stress responses.

Journal of Integrative Plant Biology, 2019
In eukaryotic cells, the expression of protein-coding genes is greatly influenced by the dynamic chromatin environment. Epigenetic mechanisms, including covalent modifications to DNA and histone tails and the accessibility of chromatin, create various ...
Yanan Chang, Chen Zhu, Jing Jiang, Huiming Zhang, Jian‐Kang Zhu, Cheng-Guo Duan   +5 more
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source