Results 211 to 220 of about 8,100,350 (339)
Molecular Mechanisms of Gene Expression Regulation in Response to Heat Stress in <i>Hemerocallis fulva</i>. [PDF]
Chu B, Liu W, Li J, Zhang X, Li P.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Mechanisms and therapeutic implications of gene expression regulation by circRNA-protein interactions in cancer. [PDF]
Zhang N +7 more
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Dynamic Chromatin Accessibility and Gene Expression Regulation During Maize Leaf Development. [PDF]
Wang Y, Wang S, Wu Y, Cheng J, Wang H.
europepmc +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Gene Expression Regulation and the Signal Transduction of Programmed Cell Death. [PDF]
Saqirile +5 more
europepmc +1 more source

