Results 191 to 200 of about 8,100,350 (339)

Convergent Transcriptional Regulation of Endothelial Dysfunction by Oxidative Stress and Inflammatory Stimulation: A Multi-Dataset Gene Expression Meta-Analysis

Dayakshin Arumugam
openalex   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Developmental chromatin context shapes SPT5 regulation of promoter-proximal Pol II, fine-tuning dynamic changes in gene expression - Bioinformatics Pipelines & Analysis Scripts

Alessandro Dulja, Marvin Mayer, Niklas L Engel, Arkadiy K. Golov, Katharina Bender, Mattia Forneris, Yacine Kherdjemil, Songjie Feng, Rebecca R. Viales, Eileen E. M. Furlong   +9 more
openalex   +2 more sources

A mechanism of global gene expression regulation is disrupted by multiple disease states and drug treatments. [PDF]

PLoS One
Pickard BS.
europepmc   +1 more source

Gene Expression Regulation in Airway Pathogens: Importance for Otitis Media. [PDF]

Front Cell Infect Microbiol, 2022
Janoušková M, Straw ML, Su YC, Riesbeck K.   +3 more
europepmc   +1 more source

Genome-wide identification of GhAOX gene family and its expression and regulation in cotton CMS line Jin A

Jinlong Zhang, Li Zhang, Yuekai Su, Jinjiang Shi, Junfang Yang, Xiuqing Yang, Jinling Huang, Yunfang Qu   +7 more
openalex   +1 more source

Epigenetic Regulation of Divergent Co-Expression Between Whole-Genome Duplication and Transposed Duplication Genes and Its Impact on Catechin Accumulation in Camellia sinensis

Shuaibin Lian, Huajin Feng, Haojie Hou, Liang Zhang (41392), Youchao Tu, Ke Gong, Wei Zhang   +6 more
openalex   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Modification of the BphP1-QPAS1 optogenetic system for gene expression regulation in Nicotiana benthamiana tobacco leaves using near-infrared light. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Surkova ES, Galimova YA, Battulina NV, Motorina DM, Omelina ES.   +4 more
europepmc   +1 more source

Dental and Orthopaedic Implant Loosening: Overlap in Gene Expression Regulation. [PDF]

Front Immunol, 2022
Schluessel S, Hartmann ES, Koehler MI, Beck F, Redeker JI, Saller MM, Akova E, Krebs S, Holzapfel BM, Mayer-Wagner S.   +9 more
europepmc   +1 more source