Results 181 to 190 of about 8,100,350 (339)

Transcriptional regulation drives heteroresistance in Pseudomonas aeruginosa : evidence from genomic and targeted gene expression analysis

Weijie Feng, Jia Hou, Gang Li, He Yin, Tiantian Dang, Guangqi Li, Jiaming Li, Min Li, Chunhua Song, Sean X. Leng, Zhijun Zhao   +10 more
openalex   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The genetic architecture of gene expression regulation in a <i>Citrus x Poncirus</i> hybrid tolerant to Huanglongbing. [PDF]

Front Plant Sci
Diaz IA, Zayed O, Ávila De Dios E, Jiang C, Bowman KD, Seymour DK.   +5 more
europepmc   +1 more source

SLU7: A New Hub of Gene Expression Regulation-From Epigenetics to Protein Stability in Health and Disease. [PDF]

Int J Mol Sci, 2022
Gárate-Rascón M, Recalde M, Rojo C, Fernández-Barrena MG, Ávila MA, Arechederra M, Berasain C.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Nuclear functional role of metabolic enzymes and related metabolites: Focus on gene expression regulation. [PDF]

Mol Metab
Todisco S, Iacobazzi D, Santarsiero A, Convertini P, Infantino V.   +4 more
europepmc   +1 more source

Global Gene Expression Regulation Mediated by TGFβ Through H3K9me3 Mark. [PDF]

Cancer Inform, 2022
Naik A, Dalpatraj N, Thakur N.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Elucidating the role of mycobacteriophage D29-encoded Gp36 in DNA binding and phage gene expression regulation. [PDF]

Nucleic Acids Res
Pillai SS, Jain V.
europepmc   +1 more source

Nutritional compensation of the circadian clock is a conserved process influenced by gene expression regulation and mRNA stability. [PDF]

PLoS Biol, 2023
Kelliher CM, Stevenson EL, Loros JJ, Dunlap JC.   +3 more
europepmc   +1 more source