Results 171 to 180 of about 8,100,350 (339)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

A Novel mechanism for depot-specific leptin gene expression regulation and its persistence after weight loss. [PDF]

iScience
Taege N, Britsemmer JH, Israel A, Krause C, Junge S, Feuchtinger A, Ussar S, Pfluger PT, Gemoll T, Schriever SC, Kirchner H.   +10 more
europepmc   +1 more source

Development of chloroplast transformation and gene expression regulation technology in land plants. [PDF]

Front Plant Sci, 2022
An Y, Wang Y, Wang X, Xiao J.
europepmc   +1 more source

Analyzing Post-transcriptional Regulation in Stochastic Gene Expression Models Using Partitioned Poisson Arrivals [PDF]

K. W. Wong, Argenis Arriojas, Sho Inaba, Hodjat Pendar, Abhyudai Singh, Rahul Kulkarni   +5 more
openalex   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The Nutritional Gene Expression Regulation Potential of a Lysolecithin-Based Product. [PDF]

Curr Issues Mol Biol
Van Hoeck V, Spaepen R, Forier B.
europepmc   +1 more source

Predictive modeling of gene expression regulation. [PDF]

BMC Bioinformatics, 2021
Regondi C, Fratelli M, Damia G, Guffanti F, Ganzinelli M, Matteucci M, Masseroli M.   +6 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Adaptation to Nighttime Light via Gene Expression Regulation in <i>Drosophila suzukii</i>. [PDF]

Ecol Evol
Takenaka N, Takahashi Y.
europepmc   +1 more source

Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor. [PDF]

J Biol Chem, 2023
Burghi V, Paradis JS, Officer A, Adame-Garcia SR, Wu X, Matthees ESF, Barsi-Rhyne B, Ramms DJ, Clubb L, Acosta M, Tamayo P, Bouvier M, Inoue A, von Zastrow M, Hoffmann C, Gutkind JS.   +15 more
europepmc   +1 more source