Results 241 to 250 of about 2,705,095 (358)

RBM22, a Key Player of Pre-mRNA Splicing and Gene Expression Regulation, Is Altered in Cancer. [PDF]

Cancers (Basel), 2022
Soubise B, Jiang Y, Douet-Guilbert N, Troadec MB.   +3 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Epigenetic inheritance and gene expression regulation in early Drosophila embryos. [PDF]

EMBO Rep
Ciabrelli F, Atinbayeva N, Pane A, Iovino N.   +3 more
europepmc   +1 more source

Uncovering Divergence in Gene Expression Regulation in the Adaptation of Yeast to Nitrogen Scarcity. [PDF]

mSystems, 2021
Villarroel CA, Bastías M, Canessa P, Cubillos FA.   +3 more
europepmc   +1 more source

Regulation of Spi 2.1 and 2.2 gene expression after turpentine inflammation: discordant responses to IL-6 [PDF]

, 1999
Susan A. Berry, Pearl L. Bergad, Allison M. Stolz, Howard C. Towle, Sarah Jane Schwarzenberg   +4 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Integrated Genomic Analysis Reveals the Impact of Avermectin on Chromatin Structure and Gene Expression Regulation in <i>Bombyx mori</i>. [PDF]

Insects
Guo Y, Zhang T, Lu W, Liu D, Lao J, Zhang N, Sun H, Jia L, Ma S.   +8 more
europepmc   +1 more source

Prediction of gene expression regulation by human microRNAs in Plasmodium falciparum. [PDF]

Genes Environ, 2021
Grinev A, Fokina N, Bogomolov D, Berechikidze I, Lazareva Y.   +4 more
europepmc   +1 more source

Regulation of Ether À-Go-Go-1 Potassium Channel (EAG1) Gene Expression by Serum and TGF-Alpha in Human Liver Cancer Cells [PDF]

, 2013
Muñoz Acuña, Cleber Camacho, María Eugenia Mendoza‐Garrido   +2 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source