Results 81 to 90 of about 1,893,780 (318)

Regulation of virulence gene expression [PDF]

Virulence, 2014
The bacterial pathogen that finds itself, either by accident or design, within the human or animal host, senses and adapts to the prevailing conditions by modulating its gene expression on a global...
Thomas, M.S., Wigneshweraraj, S.
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The use of general and specific combining abilities in a context of gene expression relevant to plant breeding

, 2008
Many common traits are believed to be a composite reflection of multiple genetic and environmental factors. Recent advances suggest that subtle variations in the regulation of gene expression may contribute to quantitative traits.
Vuylsteke, M., Eeuwijk, F.A., van
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

TcZC3HTTP, a regulatory element that contributes to Trypanosoma cruzi cell proliferation

Microbiology Spectrum
Post-transcriptional regulation of gene expression is a critical process for adapting to and surviving Trypanosoma cruzi, a parasite with a complex life cycle.
Bruno Accioly Alves Romagnoli, Aline Castro Rodrigues Lucena, Eden Ribeiro Freire, Isadora Filipaki Munhoz da Rocha, Lysangela Ronalte. Alves, Samuel Goldenberg   +5 more
doaj   +1 more source

Molecular Basis of the Function of Transcriptional Enhancers

Cells, 2020
Transcriptional enhancers are major genomic elements that control gene activity in eukaryotes. Recent studies provided deeper insight into the temporal and spatial organization of transcription in the nucleus, the role of non-coding RNAs in the process ...
Airat N. Ibragimov, Oleg V. Bylino, Yulii V. Shidlovskii   +2 more
doaj   +1 more source

Nuclear Photosynthetic Gene Expression Is Synergistically Modulated by Rates of Protein Synthesis in Chloroplasts and Mitochondria [PDF]

, 2006
Arabidopsis thaliana mutants prors1-1 and -2 were identified on the basis of a decrease in effective photosystem II quantum yield. Mutations were localized to the 5'-untranslated region of the nuclear gene PROLYL-tRNA SYNTHETASE1 (PRORS1), which acts in ...
Leister, Dario, Masiero, Simona, H. P. Braun, Pesaresi, Paolo, Braun, Hans-Peter, E. Glaser, D. Leister, Glaser, Elzbieta, Bhushan, Shashi, F. Salamini, H. Eubel, Eubel, Holger, S. Bhushan, Salamini, Francesco, P. Pesaresi, S. Masiero   +15 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Evolution of Regulated Transcription

Cells, 2020
The genomes of all organisms abound with various cis-regulatory elements, which control gene activity. Transcriptional enhancers are a key group of such elements in eukaryotes and are DNA regions that form physical contacts with gene promoters and ...
Oleg V. Bylino, Airat N. Ibragimov, Yulii V. Shidlovskii   +2 more
doaj   +1 more source

Acute phase induction of the human C-reactive protein gene in transgenic mice

, 1987
Regulation of human C-reactive protein ...
ARCONE, Rosaria
core