Results 1 to 10 of about 11,121,866 (385)
Biomolecular Concepts, 2014 MDM2 is an oncoprotein that blocks p53 tumor suppressor-mediated transcriptional transactivation, escorts p53 from the cell nucleus to the cytoplasm, and polyubiquitylates p53.
Mendoza Michael +2 more
doaj +3 more sources
Journal of Lipid Research, 2002 Development of the lipase gene family spans the change in science that witnessed the birth of contemporary techniques of molecular biology. Amino acid sequencing of enzymes gave way to cDNA cloning and gene organization, augmented by in vitro expression ...
Howard Wong, Michael C. Schotz
doaj +4 more sources
Evolution of the RALF Gene Family in Plants: Gene Duplication and Selection Patterns
Evolutionary Bioinformatics, 2012 Rapid alkalinization factors (RALFs) are plant small peptides that could induce a rapid pH increase in the medium of plant cell suspension culture and play a critical role in plant development.
Jun Cao, Feng Shi
doaj +2 more sources
The gene family-free median of three [PDF]
arXiv, 2016 The gene family-free framework for comparative genomics aims at developing methods for gene order analysis that do not require prior gene family assignment, but work directly on a sequence similarity multipartite graph. We present a model for constructing a median of three genomes in this family-free setting, based on maximizing an objective function ...
Daniel Doerr +4 more
arxiv +11 more sources
Evolution of the FGF Gene Family [PDF]
International Journal of Evolutionary Biology, 2012 Fibroblast Growth Factors (FGFs) are small proteins generally secreted, acting through binding to transmembrane tyrosine kinase receptors (FGFRs). Activation of FGFRs triggers several cytoplasmic cascades leading to the modification of cell behavior ...
Silvan Oulion +2 more
semanticscholar +4 more sources
BMC Plant Biology, 2022 Liriodendron chinense (Lchi) is a tree species within the Magnoliaceae family and is considered a basal angiosperm. The too low or high temperature or soil drought will restrict its growth as the adverse environmental conditions, thus improving L ...
Weihuang Wu +11 more
semanticscholar +1 more source
Molecular evolution and expression divergence of three key Met biosynthetic genes in plants: CGS, HMT and MMT [PDF]
PeerJ, 2018 Methionine (Met) is an essential sulfur-containing amino acid in animals. Cereal and legume crops with limiting levels of Met represent the major food and feed sources for animals.
Man Zhao +6 more
doaj +2 more sources
Intratracheal aerosolization of viral vectors to newborn pig airways
BioTechniques, 2020 Gene therapy for airway diseases requires efficient delivery of nucleic acids to the airways. In small animal models, gene delivery reagents are commonly delivered as a bolus dose.
Ashley L Cooney, Patrick L Sinn
doaj +1 more source
Frontiers in Plant Science, 2022 Retrotransposons are the most abundant group of transposable elements (TEs) in plants, providing an extraordinarily versatile source of genetic variation.
Yanting Hu +15 more
doaj +1 more source
RAD51 Gene Family Structure and Function.
Annual Review of Genetics, 2020 Accurate DNA repair and replication are critical for genomic stability and cancer prevention. RAD51 and its gene family are key regulators of DNA fidelity through diverse roles in double-strand break repair, replication stress, and meiosis.
Braulio Bonilla +3 more
semanticscholar +1 more source