Results 1 to 10 of about 12,109,898 (215)
Journal of Lipid Research, 2002 Development of the lipase gene family spans the change in science that witnessed the birth of contemporary techniques of molecular biology. Amino acid sequencing of enzymes gave way to cDNA cloning and gene organization, augmented by in vitro expression ...
Howard Wong, Michael C. Schotz
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Definitions, 2020 A family of genes that encode enzymes that catalyze the decarboxylation of isocitrate yielding alpha-ketoglutarate and carbon dioxide. Alpha-ketoglutarate is a precursor used in the synthesis of alanine, glutamine and pyruvate, and is an important ...
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BMC Plant Biology, 2022 Liriodendron chinense (Lchi) is a tree species within the Magnoliaceae family and is considered a basal angiosperm. The too low or high temperature or soil drought will restrict its growth as the adverse environmental conditions, thus improving L ...
Weihuang Wu +11 more
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Molecular Therapy: Methods & Clinical Development, 2021 Despite significant advances in cystic fibrosis (CF) treatments, a one-time treatment for this life-shortening disease remains elusive. Stable complementation of the disease-causing mutation with a normal copy of the CF transmembrane conductance ...
Laura I. Marquez Loza +6 more
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Retinoblastoma family genes [PDF]
Oncogene, 2006 The retinoblastoma gene Rb was the first tumor suppressor gene cloned, and it is well known as a negative regulator of the cell cycle through its ability to bind the transcription factor E2F and repress transcription of genes required for S phase. Although over 100 other proteins have been reported to interact with Rb, in most cases these interactions ...
W, Du, J, Pogoriler
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Lentiviral vectors transduce lung stem cells without disrupting plasticity
Molecular Therapy: Nucleic Acids, 2021 Life-long expression of a gene therapy agent likely requires targeting stem cells. Here we ask the question: does viral vector transduction or ectopic expression of a therapeutic transgene preclude airway stem cell function?
Ashley L. Cooney +4 more
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Molecular evolution and expression divergence of three key Met biosynthetic genes in plants: CGS, HMT and MMT [PDF]
PeerJ, 2018 Methionine (Met) is an essential sulfur-containing amino acid in animals. Cereal and legume crops with limiting levels of Met represent the major food and feed sources for animals.
Man Zhao +6 more
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Frontiers in Genetics, 2023 The dirigent (DIR) gene is a key player in environmental stress response and has been identified in many multidimensional tube plant species. However, there are few studies on the StDIR gene in potato. In this study, we used genome-wide identification to
Wenqi Jia +5 more
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Gene Cluster Statistics with Gene Families [PDF]
Molecular Biology and Evolution, 2009 Identifying genomic regions that descended from a common ancestor is important for understanding the function and evolution of genomes. In distantly related genomes, clusters of homologous gene pairs are evidence of candidate homologous regions. Demonstrating the statistical significance of such "gene clusters" is an essential component of comparative ...
Raghupathy, Narayanan, Durand, Dannie
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