Results 1 to 10 of about 12,462,452 (401)

The MDM2 gene family [PDF]

open access: yesBiomolecular Concepts, 2014
MDM2 is an oncoprotein that blocks p53 tumor suppressor-mediated transcriptional transactivation, escorts p53 from the cell nucleus to the cytoplasm, and polyubiquitylates p53.
Mendoza Michael   +2 more
doaj   +3 more sources

The lipase gene family [PDF]

open access: yesJournal of Lipid Research, 2002
Development of the lipase gene family spans the change in science that witnessed the birth of contemporary techniques of molecular biology. Amino acid sequencing of enzymes gave way to cDNA cloning and gene organization, augmented by in vitro expression ...
Howard Wong, Michael C. Schotz
doaj   +4 more sources

Evolution of the RALF Gene Family in Plants: Gene Duplication and Selection Patterns

open access: yesEvolutionary Bioinformatics, 2012
Rapid alkalinization factors (RALFs) are plant small peptides that could induce a rapid pH increase in the medium of plant cell suspension culture and play a critical role in plant development.
Jun Cao, Feng Shi
doaj   +2 more sources

Evolution of the FGF Gene Family [PDF]

open access: yesInternational Journal of Evolutionary Biology, 2012
Fibroblast Growth Factors (FGFs) are small proteins generally secreted, acting through binding to transmembrane tyrosine kinase receptors (FGFRs). Activation of FGFRs triggers several cytoplasmic cascades leading to the modification of cell behavior ...
Silvan Oulion   +2 more
semanticscholar   +4 more sources

Genome-wide identification of the Liriodendron chinense WRKY gene family and its diverse roles in response to multiple abiotic stress

open access: yesBMC Plant Biology, 2022
Liriodendron chinense (Lchi) is a tree species within the Magnoliaceae family and is considered a basal angiosperm. The too low or high temperature or soil drought will restrict its growth as the adverse environmental conditions, thus improving L ...
Weihuang Wu   +11 more
semanticscholar   +1 more source

Molecular evolution and expression divergence of three key Met biosynthetic genes in plants: CGS, HMT and MMT [PDF]

open access: yesPeerJ, 2018
Methionine (Met) is an essential sulfur-containing amino acid in animals. Cereal and legume crops with limiting levels of Met represent the major food and feed sources for animals.
Man Zhao   +6 more
doaj   +2 more sources

Intratracheal aerosolization of viral vectors to newborn pig airways

open access: yesBioTechniques, 2020
Gene therapy for airway diseases requires efficient delivery of nucleic acids to the airways. In small animal models, gene delivery reagents are commonly delivered as a bolus dose.
Ashley L Cooney, Patrick L Sinn
doaj   +1 more source

Identification and Analysis of bZIP Family Genes in Potato and Their Potential Roles in Stress Responses

open access: yesFrontiers in Plant Science, 2021
The bZIP proteins comprise one of the largest transcription factor families and play important roles in plant growth and development, senescence, metabolic reactions, and stress responses.
Qi Wang   +12 more
doaj   +1 more source

RAD51 Gene Family Structure and Function.

open access: yesAnnual Review of Genetics, 2020
Accurate DNA repair and replication are critical for genomic stability and cancer prevention. RAD51 and its gene family are key regulators of DNA fidelity through diverse roles in double-strand break repair, replication stress, and meiosis.
Braulio Bonilla   +3 more
semanticscholar   +1 more source

Gene Cluster Statistics with Gene Families [PDF]

open access: yesMolecular Biology and Evolution, 2009
Identifying genomic regions that descended from a common ancestor is important for understanding the function and evolution of genomes. In distantly related genomes, clusters of homologous gene pairs are evidence of candidate homologous regions. Demonstrating the statistical significance of such "gene clusters" is an essential component of comparative ...
Dannie Durand, Narayanan Raghupathy
openaire   +2 more sources

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