Results 91 to 100 of about 7,504,063 (305)
CGM2, a Member of the Carcinoembryonic Antigen Gene Family is Down- Regulated in Colorectal Carcinomas [PDF]
We have determined the precise chromosomal location, the exon structure, and the expression pattern of CGM2, a member of the carcinoembryonic antigen (CEA) gene family.
Zimmermann, Wolfgang +7 more
core +1 more source
Aspartic proteases (APs) are among the four primary families of proteolytic enzymes found in plants, and they are essential for both stress response mechanisms and developmental activities.
Peiyang He, Lifan Huang, Hanyang Cai
doaj +1 more source
Characterization, sub-cellular localization and expression profiling of the isoprenylcysteine methylesterase gene family in Arabidopsis thaliana [PDF]
Background: Isoprenylcysteine methylesterases (ICME) demethylate prenylated protein in eukaryotic cell. Until now, knowledge about their molecular information, localization and expression pattern is largely unavailable in plant species.
Wang, H.Z. +7 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Chromosomal Localization of the Carcinoembryonic Antigen Gene Family and Differential Expression in Various Tumors [PDF]
Carcinoembryonic antigen (CEA) is a glycoprotein which is important as a tumor marker for a number of human cancers. It is a member of a gene family comprising about 10 closely related genes.
Weber, Bernhard +17 more
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Molecular biology of the Oleosin gene family of Brassica napus [PDF]
Oilseed rape (Brassica napus) is a valuable oil producing crop plant. Oil is produced by developing seeds and constitutes 45% of the dry seed weight. Storage oil is deposited as triacylglycerol in spherical structures called oil bodies.
Edwards, Eira Wyn
core
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The secretoglobins (SCGBs) comprise a family of small, secreted proteins found in animals exclusively of mammalian lineage. There are 11 human SCGB genes and five pseudogenes.
Jackson Brian C +6 more
doaj +1 more source
Contents: President’s address at the MMCFD graduation of vocational trainees, 25 March 2014 - Pierre Mallia; MMCFD Graduation Photos 25 March 2014The mission of the Journal of the Malta College of Family Doctors (JMCFD) is to deliver accurate ...
Mallia, Pierre +2 more
core

