Results 161 to 170 of about 7,804,402 (208)
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Blood, 2001
AbstractThe Krüppel-like factor(KLF) family of genes encodes transcriptional regulatory proteins that play roles in differentiation of a diverse set of cells in mammals. For instance, the founding memberKLF1 (also known as EKLF) is required for normal globin production in mammals.
Oates, A. C. +7 more
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AbstractThe Krüppel-like factor(KLF) family of genes encodes transcriptional regulatory proteins that play roles in differentiation of a diverse set of cells in mammals. For instance, the founding memberKLF1 (also known as EKLF) is required for normal globin production in mammals.
Oates, A. C. +7 more
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Adaptive evolution of genes and gene families
Current Opinion in Genetics & Development, 2003The huge influx of genomic sequence and new statistical methods is making the discovery of genes subjected to adaptive evolution increasingly common. The use of comparative genomics to identify adaptive evolution is resulting in predictions of functionally important genes and gene regions.
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β1,3-glycosyltransferase Gene Family and IGnT Gene Family
2009This section mainly reviews β1,3-glycosyltransferases (β3GT), which transfer donor substrate sugars via a β1,3-linkage, and IGnTs, which transfer donor substrate sugars via a β1,6-linkage (Hennet 2002; Narimatsu 2004; Togayachi 2006). Information such as accession numbers of these β3GTs and IGnTs are shown in Table 1.
Akira Togayachi +2 more
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Gene Structure and Gene Families
2019Approaches for the discovery of protein-coding genes were described in detail in Chap. 3. These included EST sequencing, RNA-seq, and full genome sequencing. Raw DNA sequences generated by these approaches are assembled into sets that are assumed to come from a single genetic locus. These are often called unigene sets.
David B. Neale, Nicholas C. Wheeler
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Ras-like genes and gene families in the mouse
Mammalian Genome, 1991Four human RAS-like cDNAs and a mouse genomic DNA fragment were used to define novel mouse Ras-like genes and gene families. Inheritance of DNA restriction fragment length variants associated with these genes in recombinant inbred and backcross mice allowed definition of 12 genetic loci, nine of which were mapped, to chromosomes (Chr) 2, 4, 7, 8, 9 ...
G, Drivas +4 more
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Genes and family environment in familial clustering of cancer
Theoretical Medicine, 1994Familial clustering of a disease is defined as the occurrence of the disease within some families in excess of what would be expected from the occurrence in the population. It has been demonstrated for several cancer types, ranging from rare cancers as the adenomatosis-coli-associated colon cancer or the Li-Fraumeni syndrome to more common cancers as ...
K, Borch-Johnsen +2 more
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Family reunion – The ZIP/prion gene family
Progress in Neurobiology, 2011Prion diseases are fatal neurodegenerative diseases of humans and animals which, in addition to sporadic and familial modes of manifestation, can be acquired via an infectious route of propagation. In disease, the prion protein (PrP(C)) undergoes a structural transition to its disease-causing form (PrP(Sc)) with profoundly different physicochemical ...
Sepehr, Ehsani +9 more
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Evolution of the spermadhesin gene family
Gene, 2005Spermadhesins belong to a novel family of secretory proteins of the male genital tract. They are major proteins of the seminal plasma and have been found peripherally associated to the sperm surface. So far, they have only been detected in ungulates, specifically in pig, cattle, and horse, respectively.
Bianca, Haase +6 more
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The evolution of the thrombospondin gene family
Journal of Molecular Evolution, 1993Thrombospondin-1 is an adhesive glycoprotein that is involved in cellular attachment, spreading, migration, and proliferation. To date, four genes have been identified that encode for the members of the thrombospondin gene family. These four genes are homologous to each other in the EGF-like (type 2) repeats, the calcium-binding (type 3) motifs, and ...
J, Lawler +4 more
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The mouse cornichon gene family
Development Genes and Evolution, 1999As part of a large scale mouse Expressed Sequence Tag (EST) project to identify molecules involved in the initiation of mammalian development, a homolog of the Drosophila cornichon gene was detected as a mouse maternal transcript present in the two-cell embryo.
Hwang, S Y +5 more
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