Results 201 to 210 of about 10,982,715 (232)
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BioEssays, 1998
A novel family of transcription factors that appears to play a critical role in the development of all animal species was recently uncovered on the basis of homology of the DNA binding domain of the Brachyury, or T locus, gene product. Phylogenetic studies have shown the ancient origin of this gene family, which has been named the T-box family, prior ...
Lee M. Silver, Virginia E. Papaioannou
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A novel family of transcription factors that appears to play a critical role in the development of all animal species was recently uncovered on the basis of homology of the DNA binding domain of the Brachyury, or T locus, gene product. Phylogenetic studies have shown the ancient origin of this gene family, which has been named the T-box family, prior ...
Lee M. Silver, Virginia E. Papaioannou
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Annual Review of Biochemistry, 1990
INTRODUCTION 837 FIBRIL-FORMING COLLAGENS AND THEIR GENES 839 Molecular and Supramolecular Organization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 840 The Triple -Helical Doma in ........ 841 C -Prope ptide Domain . ......... ......... 846 N-P ropeptide Domain . . . . . . . . . . . . . . .
Eero Vuorio, B de Crombrugghe
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INTRODUCTION 837 FIBRIL-FORMING COLLAGENS AND THEIR GENES 839 Molecular and Supramolecular Organization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 840 The Triple -Helical Doma in ........ 841 C -Prope ptide Domain . ......... ......... 846 N-P ropeptide Domain . . . . . . . . . . . . . . .
Eero Vuorio, B de Crombrugghe
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Trends in Biochemical Sciences, 1992
Ets proteins have a conserved DNA-binding domain and regulate transcriptional initiation from a variety of cellular and viral gene promoter and enhancer elements. Some members of the Ets family, Ets-1 and Ets-2, cooperate in transcription with the AP-1 transcription factor, the product of the proto-oncogene families, fos and jun, while others, Elk-1 ...
Kay F. Macleod +2 more
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Ets proteins have a conserved DNA-binding domain and regulate transcriptional initiation from a variety of cellular and viral gene promoter and enhancer elements. Some members of the Ets family, Ets-1 and Ets-2, cooperate in transcription with the AP-1 transcription factor, the product of the proto-oncogene families, fos and jun, while others, Elk-1 ...
Kay F. Macleod +2 more
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The myoD gene family: nodal point during specification of the muscle cell lineage.
Science, 1991The myoD gene converts many differentiated cell types into muscle. MyoD is a member of the basic-helix-loop-helix family of proteins; this 68-amino acid domain in MyoD is necessary and sufficient for myogenesis.
H. Weintraub +11 more
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Gene, 2000
In eukaryote genomes, there are many kinds of gene families. Gene duplication and conversion are sources of the evolution of gene families, including those with uniform members and those with diverse functions. Population genetics theory on identity coefficients among gene members of a gene family shows that the balance between diversification by ...
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In eukaryote genomes, there are many kinds of gene families. Gene duplication and conversion are sources of the evolution of gene families, including those with uniform members and those with diverse functions. Population genetics theory on identity coefficients among gene members of a gene family shows that the balance between diversification by ...
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On the divergence of genes in multigene families
Theoretical Population Biology, 1987Statistical properties of the amount of divergence of genes in multigene families are studied. The model considered is an infinite-site neutral model with unbiased intrachromosomal conversion, unbiased interchromosomal conversion, and recombination. By considering the time back to the most recent common ancestor of two genes, both the probability of ...
Norman L. Kaplan, Richard R. Hudson
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The cruciferin gene family in radish
Plant Molecular Biology, 1992In order to analyse the cruciferin gene family in radish a cDNA library was screened either with heterologous rapeseed probes or by differential screening and sequencing. We could identify six partial cDNA clones belonging to two different groups of cruciferin genes which do not cross-hybridize, and probably three distinct subfamilies.
Depigny-This, D. +4 more
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Gene Structure and Gene Families
2019Approaches for the discovery of protein-coding genes were described in detail in Chap. 3. These included EST sequencing, RNA-seq, and full genome sequencing. Raw DNA sequences generated by these approaches are assembled into sets that are assumed to come from a single genetic locus. These are often called unigene sets.
David B. Neale, Nicholas C. Wheeler
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Adaptive evolution of genes and gene families
Current Opinion in Genetics & Development, 2003The huge influx of genomic sequence and new statistical methods is making the discovery of genes subjected to adaptive evolution increasingly common. The use of comparative genomics to identify adaptive evolution is resulting in predictions of functionally important genes and gene regions.
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Journal of Clinical Pathology, 2020
TheSMARCAsubgroup of genes belong to the SWI1/SNF1 family that are responsible chromatin remodelling and repair. Inactivating mutations in the mainSMARCAgenesA2andA4lead to loss of expression of their respective proteins within the nucleus and, as such have characterised a set of malignancies that are underpinned by SMARCA-deficiency.The morphology of ...
Runjan Chetty, Stefano Serra
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TheSMARCAsubgroup of genes belong to the SWI1/SNF1 family that are responsible chromatin remodelling and repair. Inactivating mutations in the mainSMARCAgenesA2andA4lead to loss of expression of their respective proteins within the nucleus and, as such have characterised a set of malignancies that are underpinned by SMARCA-deficiency.The morphology of ...
Runjan Chetty, Stefano Serra
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