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SLC9/NHE gene family, a plasma membrane and organellar family of Na+/H+ exchangers [PDF]

open access: yesMolecular Aspects of Medicine, 2013
This brief review of the human Na/H exchanger gene family introduces a new classification with three subgroups to the SLC9 gene family. Progress in the structure and function of this gene family is reviewed with structure based on homology to the ...
Mark Donowitz   +2 more
exaly   +2 more sources

THE FAMILY OF COLLAGEN GENES

Annual Review of Biochemistry, 1990
INTRODUCTION 837 FIBRIL-FORMING COLLAGENS AND THEIR GENES 839 Molecular and Supramolecular Organization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 840 The Triple -Helical Doma in ........ 841 C -Prope ptide Domain . ......... ......... 846 N-P ropeptide Domain . . . . . . . . . . . . . . .
E, Vuorio, B, de Crombrugghe
openaire   +2 more sources

The sulfatase gene family

Current Opinion in Genetics & Development, 1997
During the past few years, molecular analyses have provided important insights into the biochemistry and genetics of the sulfatase family of enzymes, identifying the molecular bases of inherited diseases caused by sulfatase deficiencies. New members of the sulfatase gene family have been identified in man and other species using a genomic approach ...
PARENTI, GIANCARLO   +2 more
openaire   +5 more sources

The ets gene family

Trends in Biochemical Sciences, 1992
Ets proteins have a conserved DNA-binding domain and regulate transcriptional initiation from a variety of cellular and viral gene promoter and enhancer elements. Some members of the Ets family, Ets-1 and Ets-2, cooperate in transcription with the AP-1 transcription factor, the product of the proto-oncogene families, fos and jun, while others, Elk-1 ...
K, Macleod, D, Leprince, D, Stehelin
openaire   +2 more sources

Evolution of gene families

Gene, 2000
In eukaryote genomes, there are many kinds of gene families. Gene duplication and conversion are sources of the evolution of gene families, including those with uniform members and those with diverse functions. Population genetics theory on identity coefficients among gene members of a gene family shows that the balance between diversification by ...
openaire   +2 more sources

Adaptive evolution of genes and gene families

Current Opinion in Genetics & Development, 2003
The huge influx of genomic sequence and new statistical methods is making the discovery of genes subjected to adaptive evolution increasingly common. The use of comparative genomics to identify adaptive evolution is resulting in predictions of functionally important genes and gene regions.
openaire   +2 more sources

β1,3-glycosyltransferase Gene Family and IGnT Gene Family

2009
This section mainly reviews β1,3-glycosyltransferases (β3GT), which transfer donor substrate sugars via a β1,3-linkage, and IGnTs, which transfer donor substrate sugars via a β1,6-linkage (Hennet 2002; Narimatsu 2004; Togayachi 2006). Information such as accession numbers of these β3GTs and IGnTs are shown in Table 1.
Akira Togayachi   +2 more
openaire   +1 more source

Ras-like genes and gene families in the mouse

Mammalian Genome, 1991
Four human RAS-like cDNAs and a mouse genomic DNA fragment were used to define novel mouse Ras-like genes and gene families. Inheritance of DNA restriction fragment length variants associated with these genes in recombinant inbred and backcross mice allowed definition of 12 genetic loci, nine of which were mapped, to chromosomes (Chr) 2, 4, 7, 8, 9 ...
G, Drivas   +4 more
openaire   +2 more sources

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