Results 21 to 30 of about 11,121,866 (385)

A review of the new HGNC gene family resource

open access: yesHuman Genomics, 2016
The HUGO Gene Nomenclature Committee (HGNC) approves unique gene symbols and names for human loci. As well as naming genomic loci, we manually curate genes into family sets based on shared characteristics such as function, homology or phenotype.
Kristian A. Gray   +4 more
semanticscholar   +1 more source

Increased CFTR expression and function from an optimized lentiviral vector for cystic fibrosis gene therapy

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Despite significant advances in cystic fibrosis (CF) treatments, a one-time treatment for this life-shortening disease remains elusive. Stable complementation of the disease-causing mutation with a normal copy of the CF transmembrane conductance ...
Laura I. Marquez Loza   +6 more
doaj  

Chromosome-Scale Assembly of the Dendrobium nobile Genome Provides Insights Into the Molecular Mechanism of the Biosynthesis of the Medicinal Active Ingredient of Dendrobium

open access: yesFrontiers in Genetics, 2022
Orchids constitute approximately 10% of flowering plant species. However, only about 10 orchid genomes have been published. Metabolites are the main way through which orchids respond to their environment.
Qing Xu   +12 more
doaj   +1 more source

Genome-wide identification of Cellulose-like synthase D gene family in Dendrobium catenatum

open access: yesBiotechnology & Biotechnological Equipment, 2021
Dendrobium catenatum, which grows on the semi humid rocks in the mountains, has been at the top of the ‘Nine Immortals of China’ since ancient times. It is a kind of yin tonic medicine and its main active component is polysaccharide.
Hangxian Xi   +10 more
doaj   +1 more source

Genome-wide identification and characterization of the bHLH gene family in tomato

open access: yesBMC Genomics, 2015
BackgroundThe basic helix-loop-helix (bHLH) proteins are a large superfamily of transcription factors, and play a central role in a wide range of metabolic, physiological, and developmental processes in higher organisms.
Hua Sun, Huajie Fan, H. Ling
semanticscholar   +1 more source

Genome-wide identification, phylogeny and expression analysis of GRAS gene family in tomato

open access: yesBMC Plant Biology, 2015
GRAS transcription factors usually act as integrators of multiple growth regulatory and environmental signals, including axillary shoot meristem formation, root radial pattering, phytohormones, light signaling, and abiotic/biotic stress.
Wei Huang   +4 more
semanticscholar   +1 more source

The Eucalyptus terpene synthase gene family

open access: yesBMC Genomics, 2015
BackgroundTerpenoids are abundant in the foliage of Eucalyptus, providing the characteristic smell as well as being valuable economically and influencing ecological interactions.
C. Külheim   +7 more
semanticscholar   +1 more source

The p53 gene family [PDF]

open access: yesOncogene, 1999
p73 and p63 are two recently discovered p53 homologs. Like p53, these proteins can recognize canonical p53 DNA-binding sites and, when overproduced, can activate p53-responsive target genes and induce apoptosis. Unlike p53, these genes undergo complex alternative splicing which, at least in the case of p63, yields proteins with widely divergent ...
openaire   +3 more sources

The Caenorhabditis chemoreceptor gene families [PDF]

open access: yesBMC Biology, 2008
Chemoreceptor proteins mediate the first step in the transduction of environmental chemical stimuli, defining the breadth of detection and conferring stimulus specificity. Animal genomes contain families of genes encoding chemoreceptors that mediate taste, olfaction, and pheromone responses.
Thomas, James H., Robertson, Hugh M.
openaire   +5 more sources

Lentiviral vectors transduce lung stem cells without disrupting plasticity

open access: yesMolecular Therapy: Nucleic Acids, 2021
Life-long expression of a gene therapy agent likely requires targeting stem cells. Here we ask the question: does viral vector transduction or ectopic expression of a therapeutic transgene preclude airway stem cell function?
Ashley L. Cooney   +4 more
doaj  

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