Results 1 to 10 of about 1,189,577 (306)

Genetic Limitation and Conservation Implications in Tetracentron sinense: SNP-Based Analysis of Spatial Genetic Structure and Gene Flow [PDF]

open access: yesBiology
The present research investigates the fine-scale spatial genetic structure (SGS) and gene flow dynamics in the endangered relict tree Tetracentron sinense, a keystone species in China’s montane ecosystems facing severe habitat fragmentation and genetic ...
Xiaojuan Liu   +5 more
doaj   +2 more sources

Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Background Pediatric high-grade gliomas (pHGGs) are among the most common and incurable malignant neoplasms of childhood. Despite aggressive, multimodal treatment, the outcome of children with high-grade gliomas has not significantly improved over the ...
Malcolm K Brenner   +15 more
doaj   +1 more source

Comparing Genetic and Field-Based Estimates of Population Connectivity in Marbled Salamanders, Ambystoma opacum

open access: yesDiversity, 2022
Estimating connectivity is key for maintaining population viability for pond-breeding amphibians, especially in areas where habitat alterations occur. Here, we used genetic data (microsatellites) to estimate connectivity of marbled salamanders, Ambystoma
Karine E. Posbic-Leydet   +4 more
doaj   +1 more source

Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis

open access: yesFrontiers in Physiology, 2020
Chronic pancreatitis, a known risk factor for the development of pancreatic ductal adenocarcinoma (PDA), is a serious, widespread medical condition characterized by inflammation, fibrosis, and acinar to ductal metaplasia (ADM).
Kathleen E. DelGiorno   +9 more
doaj   +1 more source

Ageratum yellow vein alphasatellite and tomato leaf curl Java betasatellite association with begomoviruses infecting crops and weeds in Indonesia

open access: yesPlant Protection Science, 2023
Symptomatic samples were taken from five districts in Yogyakarta and Central Java provinces of Indonesia to survey the genetic diversity of Begomovirus, α and β satellites.
Adyatma Irawan Santosa   +1 more
doaj   +1 more source

Population Genomics of Domesticated Cucurbita ficifolia Reveals a Recent Bottleneck and Low Gene Flow with Wild Relatives

open access: yesPlants, 2023
Cucurbita ficifolia is a squash grown from Mexico to Bolivia. Its ancestor is unknown, but it has limited compatibility with wild xerophytic Cucurbita from Mexico’s highlands. We assembled the reference genome of C.
Xitlali Aguirre-Dugua   +10 more
doaj   +1 more source

Genealogy-based methods for inference of historical recombination and gene flow and their application in Saccharomyces cerevisiae [PDF]

open access: yes, 2012
Genetic exchange between isolated populations, or introgression between species, serves as a key source of novel genetic material on which natural selection can act.
Brem, Rachel B.   +11 more
core   +1 more source

Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS

open access: yeseLife, 2017
The temporal regulation of protein abundance and post-translational modifications is a key feature of cell division. Recently, we analysed gene expression and protein abundance changes during interphase under minimally perturbed conditions (Ly et al ...
Tony Ly   +8 more
doaj   +1 more source

Genomic-based epidemiology reveals independent origins and gene flow of glyphosate resistance in Bassia scoparia populations across North America [PDF]

open access: yes, 2021
Genomic-based epidemiology can provide insight into the origins and spread of herbicide resistance mechanisms in weeds. We used kochia (Bassia scoparia) populations resistant to the herbicide glyphosate from across western North America to test the ...
Ravet, K.   +48 more
core   +1 more source

Targeted gene flow for conservation [PDF]

open access: yesConservation Biology, 2015
Abstract Anthropogenic threats often impose strong selection on affected populations, causing rapid evolutionary responses. Unfortunately, these adaptive responses are rarely harnessed for conservation. We suggest that conservation managers pay close attention to adaptive processes and geographic variation, with an eye to using them ...
Ella, Kelly, Ben L, Phillips
openaire   +2 more sources

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