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Genetic Limitation and Conservation Implications in Tetracentron sinense: SNP-Based Analysis of Spatial Genetic Structure and Gene Flow [PDF]

open access: yesBiology
The present research investigates the fine-scale spatial genetic structure (SGS) and gene flow dynamics in the endangered relict tree Tetracentron sinense, a keystone species in China’s montane ecosystems facing severe habitat fragmentation and genetic ...
Xiaojuan Liu   +5 more
doaj   +2 more sources

Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Background Pediatric high-grade gliomas (pHGGs) are among the most common and incurable malignant neoplasms of childhood. Despite aggressive, multimodal treatment, the outcome of children with high-grade gliomas has not significantly improved over the ...
Malcolm K Brenner   +15 more
doaj   +1 more source

Comparing Genetic and Field-Based Estimates of Population Connectivity in Marbled Salamanders, Ambystoma opacum

open access: yesDiversity, 2022
Estimating connectivity is key for maintaining population viability for pond-breeding amphibians, especially in areas where habitat alterations occur. Here, we used genetic data (microsatellites) to estimate connectivity of marbled salamanders, Ambystoma
Karine E. Posbic-Leydet   +4 more
doaj   +1 more source

Genomic signatures of host-associated divergence and adaptation in a coral-eating snail, Coralliophila violacea (Kiener, 1836). [PDF]

open access: yes, 2020
The fluid nature of the ocean, combined with planktonic dispersal of marine larvae, lowers physical barriers to gene flow. However, divergence can still occur despite gene flow if strong selection acts on populations occupying different ecological niches.
Barber, Paul H   +4 more
core   +1 more source

Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis

open access: yesFrontiers in Physiology, 2020
Chronic pancreatitis, a known risk factor for the development of pancreatic ductal adenocarcinoma (PDA), is a serious, widespread medical condition characterized by inflammation, fibrosis, and acinar to ductal metaplasia (ADM).
Kathleen E. DelGiorno   +9 more
doaj   +1 more source

Ageratum yellow vein alphasatellite and tomato leaf curl Java betasatellite association with begomoviruses infecting crops and weeds in Indonesia

open access: yesPlant Protection Science, 2023
Symptomatic samples were taken from five districts in Yogyakarta and Central Java provinces of Indonesia to survey the genetic diversity of Begomovirus, α and β satellites.
Adyatma Irawan Santosa   +1 more
doaj   +1 more source

Population Genomics of Domesticated Cucurbita ficifolia Reveals a Recent Bottleneck and Low Gene Flow with Wild Relatives

open access: yesPlants, 2023
Cucurbita ficifolia is a squash grown from Mexico to Bolivia. Its ancestor is unknown, but it has limited compatibility with wild xerophytic Cucurbita from Mexico’s highlands. We assembled the reference genome of C.
Xitlali Aguirre-Dugua   +10 more
doaj   +1 more source

Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS

open access: yeseLife, 2017
The temporal regulation of protein abundance and post-translational modifications is a key feature of cell division. Recently, we analysed gene expression and protein abundance changes during interphase under minimally perturbed conditions (Ly et al ...
Tony Ly   +8 more
doaj   +1 more source

Genome-wide tests for introgression between cactophilic Drosophila implicate a role of inversions during speciation [PDF]

open access: yes, 2015
K.L. was funded by a junior research fellowship from the National Environmental Research Council, UK (NE/I020288/1, NBAF659).Models of speciation-with-gene-flow have shown that the reduction in recombination between alternative chromosome arrangements ...
Clarke, M.   +3 more
core   +3 more sources

Polyploidy breaks speciation barriers in Australian burrowing frogs Neobatrachus [PDF]

open access: yes, 2020
Polyploidy has played an important role in evolution across the tree of life but it is still unclear how polyploid lineages may persist after their initial formation.
Booker, William   +11 more
core   +4 more sources

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