Results 1 to 10 of about 1,168,362 (261)

Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas

Journal for ImmunoTherapy of Cancer, 2021
Background Pediatric high-grade gliomas (pHGGs) are among the most common and incurable malignant neoplasms of childhood. Despite aggressive, multimodal treatment, the outcome of children with high-grade gliomas has not significantly improved over the ...
Malcolm K Brenner, Valentina Hoyos, Ignazio Caruana, Gerrit Weber, Claudia Manuela Arnone, Vinicia Assunta Polito, Angela Mastronuzzi, Andrea Carai, Francesca Camassei Diomedi, Laura Antonucci, Maria Vinci, Francesco Ferrari, Elisa Salviato, Marco Scarsella, Cristiano De Stefanis, Lucia Lisa Petrilli   +15 more
doaj   +1 more source

Comparing Genetic and Field-Based Estimates of Population Connectivity in Marbled Salamanders, Ambystoma opacum

Diversity, 2022
Estimating connectivity is key for maintaining population viability for pond-breeding amphibians, especially in areas where habitat alterations occur. Here, we used genetic data (microsatellites) to estimate connectivity of marbled salamanders, Ambystoma
Karine E. Posbic-Leydet, Kelsey L. Glennon, Jolene T. Fisher, Don R. Church, Sheri A. Church   +4 more
doaj   +1 more source

Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis

Frontiers in Physiology, 2020
Chronic pancreatitis, a known risk factor for the development of pancreatic ductal adenocarcinoma (PDA), is a serious, widespread medical condition characterized by inflammation, fibrosis, and acinar to ductal metaplasia (ADM).
Kathleen E. DelGiorno, Razia F. Naeem, Linjing Fang, Chi-Yeh Chung, Cynthia Ramos, Natalie Luhtala, Carolyn O’Connor, Tony Hunter, Uri Manor, Geoffrey M. Wahl   +9 more
doaj   +1 more source

Ageratum yellow vein alphasatellite and tomato leaf curl Java betasatellite association with begomoviruses infecting crops and weeds in Indonesia

Plant Protection Science, 2023
Symptomatic samples were taken from five districts in Yogyakarta and Central Java provinces of Indonesia to survey the genetic diversity of Begomovirus, α and β satellites.
Adyatma Irawan Santosa, Susamto Somowiyarjo   +1 more
doaj   +1 more source

Population Genomics of Domesticated Cucurbita ficifolia Reveals a Recent Bottleneck and Low Gene Flow with Wild Relatives

Plants, 2023
Cucurbita ficifolia is a squash grown from Mexico to Bolivia. Its ancestor is unknown, but it has limited compatibility with wild xerophytic Cucurbita from Mexico’s highlands. We assembled the reference genome of C.
Xitlali Aguirre-Dugua, Josué Barrera-Redondo, Jaime Gasca-Pineda, Alejandra Vázquez-Lobo, Andrea López-Camacho, Guillermo Sánchez-de la Vega, Gabriela Castellanos-Morales, Enrique Scheinvar, Erika Aguirre-Planter, Rafael Lira-Saade, Luis E. Eguiarte   +10 more
doaj   +1 more source

Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS

eLife, 2017
The temporal regulation of protein abundance and post-translational modifications is a key feature of cell division. Recently, we analysed gene expression and protein abundance changes during interphase under minimally perturbed conditions (Ly et al ...
Tony Ly, Arlene Whigham, Rosemary Clarke, Alejandro J Brenes-Murillo, Brett Estes, Diana Madhessian, Emma Lundberg, Patricia Wadsworth, Angus I Lamond   +8 more
doaj   +1 more source

Genome‐scale phylogeography resolves the native population structure of the Asian longhorned beetle, Anoplophora glabripennis (Motschulsky)

Evolutionary Applications, 2022
Human‐assisted movement has allowed the Asian longhorned beetle (ALB, Anoplophora glabripennis (Motschulsky)) to spread beyond its native range and become a globally regulated invasive pest.
Mingming Cui, Yunke Wu, Marion Javal, Isabelle Giguère, Géraldine Roux, Jose A. Andres, Melody Keena, Juan Shi, Baode Wang, Evan Braswell, Scott E. Pfister, Richard Hamelin, Amanda Roe, Ilga Porth   +13 more
doaj   +1 more source

Local thermal adaptation and limited gene flow constrain future climate responses of a marine ecosystem engineer

Evolutionary Applications, 2020
Rising ocean temperatures and extreme temperature events have precipitated declines and local extinctions in many marine species globally, but patterns of loss are often uneven across species ranges for reasons that are poorly understood.
Adam D. Miller, Melinda A. Coleman, Jennifer Clark, Rachael Cook, Zuraya Naga, Martina A. Doblin, Ary A. Hoffmann, Craig D. H. Sherman, Alecia Bellgrove   +8 more
doaj   +1 more source

Genetic variation within and among naturally regenerating populations of alder (Alnus glutinosa)

Acta Societatis Botanicorum Poloniae, 2011
To assess the inter- and intrapopulation genetic variation in the filial generation (F1) of alder (Alnus glutinosa (L.) Gaertn.), 11 naturally regenerated populations were analysed. Their parental populations (P), represent the whole Polish territory and
Leon Mejnartowicz
doaj   +1 more source

Cultivation, varietal structure and possibilities for cross-pollination of Brassica napus L. in Slovenia

Acta Agriculturae Slovenica, 2011
Oilseed rape, Brassica napus L., is one of the most important oil plants of the moderate climatic zone and a typical industrial plant. In the past, dynamics of oilseed rape production in Slovenia was reflected in flexible agricultural market situation ...
Barbara PIPAN, Jelka ŠUŠTAR-VOZLIČ, Vladimir MEGLIČ   +2 more
doaj   +1 more source