Results 111 to 120 of about 1,747,624 (329)
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Revista Brasileira de Zootecnia, 2016 The objective of the present work was to identify and validate single nucleotide variations located in candidate genes to growth traits in tilapia (Oreochromis niloticus). Two transitions were identified in the promoter region of the growth hormone gene (
Breidy Lizeth Cuevas-Rodríguez +5 more
doaj +1 more source
On sojourn times at particular gene frequencies
Genetical Research, 1975 SUMMARYThe distribution of visits to a particular gene frequency in a finite population of sizeNwith non-overlapping generations is derived. It is shown, by using well-known results from the theory of finite Markov chains, that all such distributions are geometric, with parameters dependent only on the set ofbij's, wherebijis the mean number of visits ...
Edward Pollak, Barry C. Arnold
openaire +3 more sources
FEBS Letters, EarlyView.Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel +2 more
wiley +1 more source
FEBS Letters, EarlyView.Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston +7 more
wiley +1 more source
Turkish Journal of Agriculture: Food Science and Technology, 2016 Toll-like receptors (TLRs) play an important role in non-specific immunity against different infectious agents such as bacterium or parasite. The aim of this work was to investigate the allele and genotype frequencies of three single-nucleotide ...
Mehmet Ulaş Çınar +3 more
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Quantifying literature citations, index terms, and Gene Ontology annotations in the Saccharomyces Genome Database to assess results-set clustering utility [PDF]
, 2006 A set of 37,325 unique literature citations was identified from 120,078 literature-based annotations in the Saccharomyces Genome Database (SGD). The citations, gene products, and related Gene Ontology (GO) annotations were analyzed to quantify unique ...
MacMullen, W. John
core
Experimental Studies of the Distribution of Gene Frequencies in Very Small Populations of Drosophila melanogaster: I. Forked [PDF]
, 1954 Warwick Estevam Kerr, Sewall Wright
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Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source