Results 191 to 200 of about 11,790,132 (329)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Multiple Chemical Sensitivity and the SLC Gene Superfamily: A Case-Control Study. [PDF]

Int J Mol Sci
Alcorta E, Gomez-Diaz C.
europepmc   +1 more source

Effect of misspecification of gene frequency on the two-point LOD score

European Journal of Human Genetics, 2001
D. Pal, M. Durner, D. Greenberg
semanticscholar   +1 more source

Frequency of Three Hemochromatosis Gene Mutations in Antalya, Turkey

Balkan Journal of Medical Genetics, 2007
Oztürk S, Lüleci G, Keser I
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

A dataset of estimated heterozygous individual and carrier couple frequencies for pan-ancestry carrier screening. [PDF]

Data Brief
Gruzin MJ, Hobbs M, Poll S, Aradhya S, Burnett L.   +4 more
europepmc   +1 more source

Organization of Immunoglobulin Genes: Reiteration Frequency of the Mouse κ Chain Constant Region Gene

, 1974
Tasuku Honjo, Seymour Packman, Daniel Swan, Marion M. Nau, Philip Leder   +4 more
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

High-frequency transformation of yeast by plasmids containing the cloned yeast ARG4 gene

, 1979
Chu-Lai Hsiao, John Carbon
openalex   +1 more source

Frequency analysis of functional immunoglobulin C and V gene expression in murine B cells at various ages. [PDF]

, 1983
Herbert Hooijkaas, A.A. Preesman, A. van Oudenaren, R. Benner, J.J. Haaijman   +4 more
openalex   +1 more source