Results 191 to 200 of about 1,747,624 (329)

Treatment of <i>E. coli</i> Infections with T4-Related Bacteriophages Belonging to Class <i>Caudoviricetes</i>: Selecting Phage on the Basis of Their Generalized Transduction Capability. [PDF]

Viruses
Nikulina AN, Nikulin NA, Suzina NE, Zimin AA.   +3 more
europepmc   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

A MUTANT GENE MAINTAINED AT HIGH FREQUENCY IN SPITE OF COMPLETE SELECTION AGAINST THE HOMOZYGOTE

, 1968
Peter S. Dawson
openalex   +2 more sources

Gene frequencies of an isolated population of Drosophila pseudoobscura [PDF]

, 1978
Lawrence G. Harshman, Charles Taylor
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Frequency of chlorophyll-deficient and other detrimental genes in Japanese populations of buckwheat, Fagopyrum esculentum Moench.

, 1979
Ohmi Ohnishi
openalex   +2 more sources

Detection of a high frequency RsaI polymorphism in the human pro alpha 2(I) collagen gene which is linked to an autosomal dominant form of osteogenesis imperfecta. [PDF]

, 1985
Anne Grobler, Gillian A. Wallis, Diana K. Brebner, Peter Beighton, A J Bester, Christopher G. Mathew   +5 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

The Frequency of CYP2C19&ast;2 Gene Polymorphisms in Burkina Faso Patients Treated with Clopidogrel

The Application of Clinical Genetics
Yves Donald Kagambèga,1,2,&ast; Abdoul Karim Ouattara,1,2,&ast; Teega-Wendé Clarisse Ouédraogo,2,3 Lassina Traoré,2,3 Nobila Valentin Yaméogo,4 Jacques Simpore1,2 1Biological Sciences, Université Norbert Zongo/ Centre Universitaire de Manga ...
Kagambèga YD, Ouattara AK, Ouédraogo TWC, Traoré L, Yaméogo NV, Simpore J   +5 more
doaj  

Frequency and Types of Point Mutation at the 12th Codon of the c‐Ki‐ras Gene Found in Pancreatic Cancers from Japanese Patients [PDF]

, 1989
Mariko Mariyama, Kiyozo Kishi, Kozo Nakamura, Hiroshi Obata, Susumu Nishimura   +4 more
openalex   +1 more source