Results 201 to 210 of about 14,201,582 (335)

Prevalence of oral streptococci and glucosyltransferase genes in mother-child pairs: a cross-sectional study in Turkish families. [PDF]

BMC Pediatr
Seker O, Duran N, Kose HD, Çolak EY, Bilmez ZY, Bolgul B, Dağli S.   +6 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Obesity-associated gene mutations across cancer types: a pan-cancer analysis of TCGA data. [PDF]

BJC Rep
Porcelli G, Brancaccio RN, Di Bella S, D'Accardo C, Orilio F, Pantina VD, Modica C, Verona F, Bianca P, Morgante C, Di Franco S, Gaggianesi M, Veschi V, Stassi G, Turdo A, Todaro M.   +15 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Functional insights into dispensable genes using genome-wide loss-of-function burden tests in Arabidopsis. [PDF]

Plant Cell
Zhao K, Lensink M, Monroe JG.
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Enhancement of RecET-mediated in vivo linear DNA assembly by a xonA mutation. [PDF]

PLoS One
Sawitzke JA, Costantino N, Caballero AC, Hutchinson E, Barenghi A, Thomason LC, Court DL.   +6 more
europepmc   +1 more source

Blood group gene frequencies.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972
T, Jenkins, G T, Nurse
openaire   +1 more source