Results 211 to 220 of about 13,063,295 (390)

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

The Frequency of CYP2C19*2 Gene Polymorphisms in Burkina Faso Patients Treated with Clopidogrel

open access: yesThe Application of Clinical Genetics
Yves Donald Kagambèga,1,2,* Abdoul Karim Ouattara,1,2,* Teega-Wendé Clarisse Ouédraogo,2,3 Lassina Traoré,2,3 Nobila Valentin Yaméogo,4 Jacques Simpore1,2 1Biological Sciences, Université Norbert Zongo/ Centre Universitaire de Manga ...
Kagambèga YD   +5 more
doaj  

The frequency of SMN gene variants lacking exon 7 and 8 is highly population dependent

open access: gold, 2019
Raymon Vijzelaar   +12 more
openalex   +2 more sources

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Hitchhiking genes and boundaries of AmpC amplicons during amoxicillin resistance development in E. coli. [PDF]

open access: yesBMC Microbiol
Nong L   +6 more
europepmc   +1 more source

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