Results 231 to 240 of about 11,790,132 (329)

An orthogonal transcription mutation system generating all transition mutations for accelerated protein evolution in vivo. [PDF]

Nat Commun
Shao M, Zhang Z, Jin X, Ding J, Chen GQ.
europepmc   +1 more source

High-frequency mutation at the adenine phosphoribosyltransferase locus in Chinese hamster ovary cells due to deletion of the gene.

, 1983
Anne E. Simon, Michael W. Taylor
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Comprehensive identification of NRG1 fusions in 25,203 patients with solid tumors. [PDF]

NPJ Precis Oncol
Xiang S, Zheng Y, Wang M, Liu X, Zhang X, Chen D, Meng G, Xu H, Wang X.   +8 more
europepmc   +1 more source

Reiteration frequency mapping: analysis of repetitive sequence organization within cloned DNA fragments containing the human initiator methionine tRNA gene.

, 1980
Michael Zasloff, T Santos
openalex   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Molecular Marker Discovery and Evaluation: EGF rs1897990 and rs1524106 Variants in a China Lung Adenocarcinoma Young Population. [PDF]

Clin Respir J
Pan H, Wang X, Zheng L, Wang J, Ding G, Zhu J, Fang Z.   +6 more
europepmc   +1 more source

The Distribution of Gene Frequencies in Populations of Polyploids [PDF]

Proceedings of the National Academy of Sciences, 1938
openaire   +3 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Genome-environment association analysis reveals climate-driven adaptation of chickens. [PDF]

Genet Sel Evol
Zhao X, Zhang J, Wen J, Zhang X, Li H, Wang H, Zhu T, Nie C, Li X, Yang W, Cao G, Xiong W, Wang X, Ning Z, Qu L.   +14 more
europepmc   +1 more source