Results 41 to 50 of about 11,790,132 (329)
Appearance frequency modulated gene set enrichment testing
BMC Bioinformatics, 2011 Background Gene set enrichment testing has helped bridge the gap from an individual gene to a systems biology interpretation of microarray data.
Sartor Maureen A, Ma Jun, Jagadish HV
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Geographic variation in walking activity in the red flour beetle Tribolium castaneum
Population Ecology, EarlyView.This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
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Gene Expression: Dialing Up the Frequency [PDF]
Current Biology, 2008 Cells often respond to external signals by altering their gene expression. The external signaling information is transduced and typically encoded in concentrations of relevant transcription factors. A recent study demonstrates that, by encoding this information in the frequency with which genes 'see' a transcription factor, the expression of hundreds ...
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FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
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Improving the efficiency of homologous recombination by chemical and biological approaches in Yarrowia lipolytica. [PDF]
PLoS ONE, 2018 Gene targeting is a challenge in Yarrowia lipolytica (Y. lipolytica) where non-homologous end-joining (NHEJ) is predominant over homologous recombination (HR). To improve the frequency and efficiency of HR in Y.
In-Seung Jang +4 more
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Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
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Study on Radio-Frequency Signal Gene Characteristics From the Perspective of Fractal Theory
IEEE Access, 2019 Radio frequency signal identification technology is a non-password authentication method based on the physical layer hardware of the device. This paper explores the feature extraction and recognition method based on the gene characteristics of the radio ...
Jingchao Li +4 more
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Genetic pattern and penetrance of polycystic kidney disease in the Western region of Iraq [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 The aims of this study are to identify the genetic pattern, estimation of gene frequency, penterance, prevalence of PKD, and to furnish an appropriate plan for genetic counselling specific for these families under investigation.
Louay Mohammed Alani
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The site frequency spectrum of dispensable genes [PDF]
Theoretical Population Biology, 2015 The differences between DNA-sequences within a population are the basis to infer the ancestral relationship of the individuals. Within the classical infinitely many sites model, it is possible to estimate the mutation rate based on the site frequency spectrum, which is comprised by the numbers $C_1,...,C_{n-1}$, where n is the sample size and $C_s$ is ...
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