Results 71 to 80 of about 1,848,340 (202)
2011 German Escherichia coli outbreak: Alignment-free whole-genome phylogeny by feature frequency profiles [PDF]
Accuracy of SNP-based whole-genome phylogeny reconstruction relies heavily on quality of sequence alignment which is particularly hindered by poorly assembled genomes. Alignment-free methods might provide additional insights. Here, we constructed a whole-
Hoi Shan Kwan +3 more
core +2 more sources
Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk [PDF]
We have previously shown that injury-induced neointima formation was rescued by adenoviral-Nogo-B gene delivery. Integrase-competent lentiviral vectors (ICLV) are efficient at gene delivery to vascular cells but present a risk of insertional mutagenesis.
Adrian J. Thrasher +11 more
core +1 more source
Background The study aimed to investigate the influence of extremely low-frequency electromagnetic fields (ELF-EMF) on clear cell renal cell carcinoma (ccRCC) by assessing alterations in gene expression and the secretion of cytokines and chemokines ...
Aleksandra Cios +7 more
doaj +1 more source
Aim: The present study was designed to investigate whether the three-apolipoprotein (AI, B, E) gene polymorphisms were related to alter their plasma protein levels and hence associated to coronary artery disease (CAD). Methods: We determined distribution
Santanu Biswas +5 more
doaj +1 more source
Gene-Mating Dynamic Evolution Theory II: Global stability of N-gender-mating polyploid systems
Extending the previous 2-gender dioecious diploid gene-mating evolution model [arXiv:1410.3456], we attempt to answer "whether the Hardy-Weinberg global stability and the exact analytic dynamical solutions can be found in the generalized N-gender N ...
Wang, Juven
core +1 more source
Transformation of the Methylotrophic Actinomycete Amycolatopis methanolica with Plasmid DNA: Stimulatory Effect of a pMEA300-Encoded Gene [PDF]
Amycolatopsis methanolica contains a 13.29-kb plasmid (pMEA300) present both in the free state and integrated at a unique genomic location. A pMEA300-free derivative (strain WV1) was selected, allowing further analysis of pMEA300-encoded functions. Whole
Dijkhuizen, L., +2 more
core +2 more sources
Background: Hospital data are a useful source of information about health status of people in a geographical location. Aim of the study: An attempt was made to extend demographic data about hemoglobin variants and their prevalence in Southwestern Nigeria
Akeem Akinboro +2 more
doaj +1 more source
FREQUENCY OF CALR GENE MUTATION IN MYELOPROLIFERATIVE NEOPLASMS
Objective: To detect the calreticulin gene mutation in myeloproliferative neoplasms and its clinicohaematological correlation. Study Design: Cross sectional study.
Sana Latif +4 more
doaj
Pathogenic bacteria present a large disease burden on human health. Control of these pathogens is hampered by rampant lateral gene transfer, whereby pathogenic strains may acquire genes conferring resistance to common antibiotics. Here we introduce tools
A. Holzinger +13 more
core +1 more source
The results from the selective validation research into the association between genetic polymorphisms and the frequency of cytogenetic abnormalities on a large independent sample are analyzed.
M. V. Khalyuzova +6 more
doaj +1 more source

