Results 71 to 80 of about 1,848,340 (202)

2011 German Escherichia coli outbreak: Alignment-free whole-genome phylogeny by feature frequency profiles [PDF]

open access: yes, 2011
Accuracy of SNP-based whole-genome phylogeny reconstruction relies heavily on quality of sequence alignment which is particularly hindered by poorly assembled genomes. Alignment-free methods might provide additional insights. Here, we constructed a whole-
Hoi Shan Kwan   +3 more
core   +2 more sources

Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk [PDF]

open access: yes, 2012
We have previously shown that injury-induced neointima formation was rescued by adenoviral-Nogo-B gene delivery. Integrase-competent lentiviral vectors (ICLV) are efficient at gene delivery to vascular cells but present a risk of insertional mutagenesis.
Adrian J. Thrasher   +11 more
core   +1 more source

Extremely low-frequency electromagnetic field (ELF-EMF) induced alterations in gene expression and cytokine secretion in clear cell renal carcinoma cells

open access: yesMedycyna Pracy
Background The study aimed to investigate the influence of extremely low-frequency electromagnetic fields (ELF-EMF) on clear cell renal cell carcinoma (ccRCC) by assessing alterations in gene expression and the secretion of cytokines and chemokines ...
Aleksandra Cios   +7 more
doaj   +1 more source

Apolipoproteins AI/B/E gene polymorphism and their plasma levels in patients with coronary artery disease in a tertiary care-center of Eastern India

open access: yesIndian Heart Journal, 2013
Aim: The present study was designed to investigate whether the three-apolipoprotein (AI, B, E) gene polymorphisms were related to alter their plasma protein levels and hence associated to coronary artery disease (CAD). Methods: We determined distribution
Santanu Biswas   +5 more
doaj   +1 more source

Gene-Mating Dynamic Evolution Theory II: Global stability of N-gender-mating polyploid systems

open access: yes, 2020
Extending the previous 2-gender dioecious diploid gene-mating evolution model [arXiv:1410.3456], we attempt to answer "whether the Hardy-Weinberg global stability and the exact analytic dynamical solutions can be found in the generalized N-gender N ...
Wang, Juven
core   +1 more source

Transformation of the Methylotrophic Actinomycete Amycolatopis methanolica with Plasmid DNA: Stimulatory Effect of a pMEA300-Encoded Gene [PDF]

open access: yes, 1995
Amycolatopsis methanolica contains a 13.29-kb plasmid (pMEA300) present both in the free state and integrated at a unique genomic location. A pMEA300-free derivative (strain WV1) was selected, allowing further analysis of pMEA300-encoded functions. Whole
Dijkhuizen, L.,   +2 more
core   +2 more sources

A retrospective study on fourteen year hemoglobin genotype variants recorded at five government hospitals in Akure, Ondo State, Southwestern Nigeria

open access: yesEgyptian Journal of Medical Human Genetics, 2016
Background: Hospital data are a useful source of information about health status of people in a geographical location. Aim of the study: An attempt was made to extend demographic data about hemoglobin variants and their prevalence in Southwestern Nigeria
Akeem Akinboro   +2 more
doaj   +1 more source

FREQUENCY OF CALR GENE MUTATION IN MYELOPROLIFERATIVE NEOPLASMS

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To detect the calreticulin gene mutation in myeloproliferative neoplasms and its clinicohaematological correlation. Study Design: Cross sectional study.
Sana Latif   +4 more
doaj  

Characterizing Scales of Genetic Recombination and Antibiotic Resistance in Pathogenic Bacteria Using Topological Data Analysis

open access: yes, 2014
Pathogenic bacteria present a large disease burden on human health. Control of these pathogens is hampered by rampant lateral gene transfer, whereby pathogenic strains may acquire genes conferring resistance to common antibiotics. Here we introduce tools
A. Holzinger   +13 more
core   +1 more source

THE VALIDATION OF THE RESULTS OF MICROARRAY STUDIES OF ASSOCIATION BETWEEN GENE POLYMORPHISMS AND THE FREQUENCY OF RADIATION EXPOSURE MARKERS

open access: yesБюллетень сибирской медицины, 2014
The results from the selective validation research into the association between genetic polymorphisms and the frequency of cytogenetic abnormalities on a large independent sample are analyzed.
M. V. Khalyuzova   +6 more
doaj   +1 more source

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