Results 81 to 90 of about 47,017 (222)

Heterologous Production of Forskolin in Tobacco (Nicotiana tabacum) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1548-1563, March 2026.
ABSTRACT Plants are promising bioreactor for the sustainable and scalable production of high‐value natural bioactive compounds, because they can synthesise phytochemicals from CO2, light, water and minerals through their innate photosynthetic carbon assimilation machinery.
Xuan Sun, Xiuming Wu, Xun Jiang, Hongmei Huang, Aiguo Yang, Yiting Li, Zhenjun Fan, Aixia Chang, Changqing Yang   +8 more
wiley   +1 more source

Global prevalence and dynamics of mecA and mecC genes in MRSA: Meta-meta-analysis, meta-regression, and temporal investigation

Journal of Infection and Public Health
This study aimed to conduct first robust meta-meta-analysis on mecC and mecA-positive MRSA strains, determining their overall prevalence and temporal trends. It encompassed 14 meta-analyses, involving 322,269 samples from 553 index studies.
Adeiza Shuaibu Suleiman, Prosun Bhattacharya, Md. Aminul Islam   +2 more
doaj   +1 more source

Bacterial resistance to antimicrobial agents and its impact on veterinary and human medicine [PDF]

, 2016
Background Antimicrobial resistance has become a major challenge in veterinary medicine, particularly in the context of bacterial pathogens that play a role in both humans and animals.
Aarestrup, Abedon, Arais, Becker, Bikard, Blondeau, Brackman, Bradford, Brandenburg, Brogden, Burrus, Bush, Bush, Bywater, Chopra, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Connell, Couto, Cuny, D'Costa, Damborg, Duijkeren, Ewers, Ewers, Falgenhauer, Feßler, Fischetti, Fuente-Núñez, Giessen, Goh, Grobbel, Grobbel, Groves, Guardabassi, Hall, Harada, Harrison, Hill, Hillier, International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG-SCC), Kadlec, Kadlec, Kadlec, Kadlec, Kehrenberg, Köck, Laube, Lefebvre, Lindsay, Lloyd, Long, Lyon, Lüthje, Maaland, Maddox, Magiorakos, Mascaretti, McCarthy, McCarthy, McNulty, Michael, Michael, Michael, Moodley, Mueller, Nienhoff, Nobrega, O'Neill, Paterson, Perreten, Poole, Putman, Ramirez, Redgrave, Richter, Riesenberg, Roberts, Roberts, Roberts, Ruiz, Rule, Schaufler, Schmiedel, Schneider, Schuch, Schultz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Scott, Shen, Sing, Soares, Sobral, Thandar, Thomas, Tsonos, van, von, Walther, Wang, Weiß, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Werckenthin, Westgarth, Westgarth, White, Wu, Zervos, Zhao, Zurek   +123 more
core   +3 more sources

Association of virulence genes with mecA gene in Staphylococcus aureus isolates from Tertiary Hospitals in Nigeria

Indian Journal of Pathology and Microbiology, 2015
Staphylococcus aureus is the etiological agent for a wide range of human infections, and its pathogenicity largely depends on various virulence factors associated with adherence, evasion of the immune system and damage of the host. This study determined the prevalence of methicillin-resistant S.
Oyebode Armstrong Terry Alli, David O Ogbolu, Adebayo O Shittu, Anthony N Okorie, John O Akinola, John B Daniel   +5 more
openaire   +3 more sources

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

Animal Research and One Health, Volume 4, Issue 1, Page 82-93, February 2026.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao, Xingyuan Ma, Ping Tian, Lianbin Li, Zafir Muhammad, Xiaokun Wang, Xuemei Xue, Jinhe Xiao, Liangjun Zheng, F. A. El‐Gohary, Xin Zhao, Junning Pu, Huping Xue   +12 more
wiley   +1 more source

Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resistant Staphylococcus aureus. [PDF]

, 2019
Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection.
Jiang, Jiandong, Li, Liang, Li, Xue, Wang, Genzhu, Wang, Xiukun, Xiong, Yan Q, You, Xuefu, Yu, Jie, Zhang, Youwen   +8 more
core  

Staphylococcal cassette chromosome mec typing and meca sequencing in methicillin-resistant staphylococci from Algeria: A highly diversified element with new mutations in mecA [PDF]

, 2016
Genetic mechanisms of methicillin resistance are still relevant in staphylococci. The aims of this study are to assess the possible exchanges of staphylococcal cassette chromosome mec (SCCmec) among isolates of methicillin-resistant staphylococci (MRS ...
Aleo, A., Benallaoua, S., Bonura, C., Djoudi, F., Mammina, C., Touati, A.   +5 more
core   +1 more source

Advances in Double‐Stranded DNA Targeting Technologies

Exploration, Volume 6, Issue 1, February 2026.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen, Yiqun Liu, Yingjie Hao, Yifan Bo, Xiaochuan Dai, Shihui Wang, Tian Xia, Xin Su, Huiyu Liu   +8 more
wiley   +1 more source

RICERCA DEL GENE mecA MEDIANTE REAL-TIME PCR IN STAPHYLOCOCCUS AUREUS

Microbiologia Medica, 2006
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S. Grasso, V. Kroumova, M.S. Caroppo, E. Grossini, P. Macaluso, P. Fonio, G. Fortina   +6 more
openaire   +3 more sources

Reversing Antibiotic Resistance: Strategies From Adjuvants to Innovative Therapeutics

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Molecular reversal strategies against antibiotic resistance act through three mechanisms: inhibiting resistance gene function, blocking horizontal gene transfer, and modulating host defense. Emerging technologies, such as CRISPR‐Cas gene editing, photodynamic therapy, nanotechnology, and ecological competition, further strengthen these approaches ...
Tianjiao Li, Fei Zeng, Jie Zhang, Yuangong Zhang, Wenjuan Yin   +4 more
wiley   +1 more source