Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind +7 more
wiley +1 more source
MarpolBase: genome database for Marchantia polymorpha featuring high quality reference genome sequences. [PDF]
Tanizawa Y +13 more
europepmc +1 more source
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink +9 more
wiley +1 more source
Proposal of <i>Allogeochorda</i> gen. nov., <i>Allogeochorda subterranea</i> comb. nov., <i>Allostigmatella</i> gen. nov. and four new combinations and <i>Allosphingorhabdus</i> gen. nov. and <i>Allosphingorhabdus lutea</i> comb. nov. as replacement names for the illegitimate genus names <i>Geochorda</i>, <i>Stigmatella</i> and <i>Alterisphingorhabdus</i> and their species. [PDF]
Kostovski M, Oren A.
europepmc +1 more source
Abstract Background Regulatory guidance in the United Kingdom advises DPYD genotyping prior to fluoropyrimidine‐based treatment. This economic evaluation estimated the costs and outcomes associated with DPYD screening prior to prescribing fluoropyrimidines for colorectal cancer in Wales and also considers additional variants to those included in ...
Catrin O. Plumpton +8 more
wiley +1 more source
Genenames.org: the HGNC and PGNC resources in 2026. [PDF]
Seal RL +5 more
europepmc +1 more source
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas +16 more
wiley +1 more source
Characterisation of the Novel HLA-DPB1*1810:01 Allele by Short-Read Next Generation Sequencing. [PDF]
Ryan O +4 more
europepmc +1 more source
Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen +14 more
wiley +1 more source
Small Signaling Peptides in <i>Sorghum bicolor</i>: Integrating Phylogeny and Gene Expression to Characterize Roles in Stem Development. [PDF]
Kurtz E, McKinley B, Mullet J.
europepmc +1 more source

