Results 191 to 200 of about 282,097 (292)

Genenames.org: the HGNC and PGNC resources in 2026. [PDF]

Nucleic Acids Res
Seal RL, Braschi B, Gray K, McClay J, Tweedie S, Bruford EA.   +5 more
europepmc   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source

'What's in a Name?' Naming Genetically Determined Movement Disorders: Gap and Controversy. [PDF]

Mov Disord
Marras C, Albanese A, Hallett M, Klein C, Lohmann K, Genetic Nomenclature in Movement Disorders Study Group Steering Committee, Jinnah HA.   +6 more
europepmc   +1 more source

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta, Luigi Angelo Fiorito, Roberta Vescovo, Anna Virgilio, Giulia Amato, Giuseppe Cimino   +5 more
wiley   +1 more source

Brain Proteomic Responses to Glucocorticoids and Their Relationship With Transcriptome: A Systematic Meta-Analysis. [PDF]

FASEB J
Juszczak GR.
europepmc   +1 more source

Pharmacogenetic CYP2B6 variants affect steroid hormone metabolism in human breast cancer cells

British Journal of Clinical Pharmacology, EarlyView.
Common genetic CYP2B6 variants correlate with adverse breast cancer outcome. The oestrogen metabolites estriol and 16‐epiestriol, which are formed downstream of CYP2B6‐catalysed 16α/β‐hydroxytestosterone, may be linked to elevated breast cancer risk and might increase due to the demonstrated CYP2B6 variants‐related metabolic shifts.
Marco Hoffmann, Julian Peter Müller, Stefan Düsterhöft, Sabrina Yamoune, Katja Susanne Just, Julia Carolin Stingl   +5 more
wiley   +1 more source

<i>Bacillus toyonensis</i> biovar Thuringiensis: an overlooked entomopathogen? [PDF]

J Bacteriol
Sauka DH, Peralta C, Del Valle EE, Palma L.   +3 more
europepmc   +1 more source

Molecular basis for Ca2+ channel diversity [PDF]

, 1994
Biel, Martin, Flockerzi, Veit, Hofmann, Franz   +2 more
core   +1 more source

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang, Jennifer A. Winton, Kyle T. Matschke, Alexandre Stouffs, Kimberly C. Lee, Yuanyuan Zhang, Wenlian Qiao, Weiwei Tan   +7 more
wiley   +1 more source

Nomenclature for Tracking of Genetic Variation of Seasonal Influenza Viruses. [PDF]

Influenza Other Respir Viruses
Neher RA, Huddleston J, Bedford T, Lewis NS, Harvey R, Galiano M, Byrne AMP, James S, Smith D, Łuksza M, Ruchnewitz D, Laessig M, Fujisaki S, Watanabe S, Hasegawa H, Hassell N, Wentworth DE, Kondor R, Deng YM, Dapat C, Subbarao K, Barr I.   +21 more
europepmc   +1 more source