Results 91 to 100 of about 7,142,455 (272)

Ontologies for the study of neurological disease [PDF]

open access: yes, 2012
We have begun work on two separate but related ontologies for the study of neurological diseases. The first, the Neurological Disease Ontology (ND), is intended to provide a set of controlled, logically connected classes to describe the range of ...
Cox, Alexander P.   +7 more
core  

Inferring meta-covariates in classification [PDF]

open access: yes, 2009
This paper develops an alternative method for gene selection that combines model based clustering and binary classification. By averaging the covariates within the clusters obtained from model based clustering, we define “meta-covariates” and use them ...
B. Hanczar   +7 more
core   +1 more source

Comparing Relational and Ontological Triple Stores in Healthcare Domain

open access: yesEntropy, 2017
Today’s technological improvements have made ubiquitous healthcare systems that converge into smart healthcare applications in order to solve patients’ problems, to communicate effectively with patients, and to improve healthcare service quality.
Ozgu Can   +3 more
doaj   +1 more source

Improving the measurement of semantic similarity by combining gene ontology and co-functional network: a random walk based approach

open access: yesBMC Systems Biology, 2018
BackgroundGene Ontology (GO) is one of the most popular bioinformatics resources. In the past decade, Gene Ontology-based gene semantic similarity has been effectively used to model gene-to-gene interactions in multiple research areas.
Jiajie Peng   +6 more
semanticscholar   +1 more source

Representation of probabilistic scientific knowledge [PDF]

open access: yes, 2013
This article is available through the Brunel Open Access Publishing Fund. Copyright © 2013 Soldatova et al; licensee BioMed Central Ltd.The theory of probability is widely used in biomedical research for data analysis and modelling.
De Grave, K   +3 more
core   +1 more source

Extending gene ontology with gene association networks [PDF]

open access: yesBioinformatics, 2015
Abstract Motivation: Gene ontology (GO) is a widely used resource to describe the attributes for gene products. However, automatic GO maintenance remains to be difficult because of the complex logical reasoning and the need of biological knowledge that are not explicitly represented in the GO.
Jiajie Peng   +5 more
openaire   +3 more sources

Discovering gene annotations in biomedical text databases

open access: yesBMC Bioinformatics, 2008
Background Genes and gene products are frequently annotated with Gene Ontology concepts based on the evidence provided in genomics articles. Manually locating and curating information about a genomic entity from the biomedical literature requires vast ...
Ozsoyoglu Gultekin, Cakmak Ali
doaj   +1 more source

Automatically linking MEDLINE abstracts to the Gene Ontology [PDF]

open access: yes, 2003
Much has been written recently about the need for effective tools and methods for mining the wealth of information present in biomedical literature (Mack and Hehenberger, 2002; Blagosklonny and Pardee, 2001; Rindflesch et al., 2002)—the activity of ...
Cleary, John G., Smith, Tony C.
core   +1 more source

The Plant Ontology facilitates comparisons of plant development stages across species [PDF]

open access: yes, 2019
The Plant Ontology (PO) is a community resource consisting of standardized terms, definitions, and logical relations describing plant structures and development stages, augmented by a large database of annotations from genomic and phenomic studies.
Cooper, Laurel   +7 more
core   +2 more sources

A gene-phenotype network for the laboratory mouse and its implications for systematic phenotyping.

open access: yesPLoS ONE, 2011
The laboratory mouse is the pre-eminent model organism for the dissection of human disease pathways. With the advent of a comprehensive panel of gene knockouts, projects to characterise the phenotypes of all knockout lines are being initiated.
Octavio Espinosa, John M Hancock
doaj   +1 more source

Home - About - Disclaimer - Privacy