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Application of Gene Ontology to Gene Identification
2011Candidate gene identification deals with associating genes to underlying biological phenomena, such as diseases and specific disorders. It has been shown that classes of diseases with similar phenotypes are caused by functionally related genes. Currently, a fair amount of knowledge about the functional characterization can be found across several ...
Bruno Tavares +4 more
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Gene ontology analysis of arthrogryposis (multiple congenital contractures)
American Journal of Medical Genetics. Part C, Seminars in Medical Genetics, 2019In 2016, we published an article applying Gene Ontology Analysis to the genes that had been reported to be associated with arthrogryposis (multiple congenital contractures) (Hall & Kiefer, 2016).
J. Kiefer, J. Hall
semanticscholar +1 more source
The ontology of the gene ontology.
AMIA ... Annual Symposium proceedings. AMIA Symposium, 2004The rapidly increasing wealth of genomic data has driven the development of tools to assist in the task of representing and processing information about genes, their products and their functions. One of the most important of these tools is the Gene Ontology (GO), which is being developed in tandem with work on a variety of bioinformatics databases.
Barry, Smith +2 more
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On ontologies for biologists: the Gene Ontology--untangling the web.
Novartis Foundation symposium, 2002The mantra of the 'post-genomic' era is 'gene function'. Yet surprisingly little attention has been given to how functional and other information concerning genes is to be captured, made accessible to biologists or structured in a computable form. The aim of the Gene Ontology (GO) Consortium is to provide a framework for both the description and the ...
Michael Ashburner, Suzanna E. Lewis
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Gene multifunctionality scoring using gene ontology
Journal of Bioinformatics and Computational Biology, 2018Multifunctional genes are important genes because of their essential roles in human cells. Studying and analyzing multifunctional genes can help understand disease mechanisms and drug discovery. We propose a computational method for scoring gene multifunctionality based on functional annotations of the target gene from the Gene Ontology. The method is
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Gene Ontology Semantic Similarity Analysis Using GOSemSim.
Methods in molecular biology, 2020Guangchuang Yu
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
exaly
Horizontal gene transfer and adaptive evolution in bacteria
Nature Reviews Microbiology, 2021Brian J Arnold, William P Hanage
exaly