Results 271 to 280 of about 7,457,987 (378)

Gene Ontology and Pathway Enrichment Analysis

, 2021
Manoj Gupta, Gayatri Gouda, S. Sabarinathan, Ravindra Donde, Goutam Kumar Dash, Ramakrishna Vadde, Lambodar Behera   +6 more
openalex   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

Improvement in genomic prediction of maize with prior gene ontology information depends on traits and environmental conditions. [PDF]

Plant Genome
Ali B, Mary-Huard T, Charcosset A, Moreau L, Rincent R.   +4 more
europepmc   +1 more source

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

QuickGO: a web-based tool for Gene Ontology searching [PDF]

, 2009
David Binns, Emily Dimmer, Rachael P. Huntley, Daniel Barrell, Claire O’Donovan, Rolf Apweiler   +5 more
openalex   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

Decoding hepatobiliary-specific immune gene patterns in gastrointestinal cancers via gene ontology fingerprints, multi-omics, and experimental integration. [PDF]

Precis Clin Med
Huang H, Zhan Y, Zong H, Huang C, Yang F, Wei Z, Qin X, Crabbe MJC, Wang Y, Zhang X.   +9 more
europepmc   +1 more source

Referee report. For: Construction and accessibility of a cross-species phenotype ontology along with gene annotations for biomedical research [v2; indexed, http://f1000r.es/2td]

, 2014
Lawrence Hunter
openalex   +1 more source

Gene Ontology annotations at SGD: new data sources and annotation methods [PDF]

, 2007
Eurie L. Hong, Rama Balakrishnan, Qing Dong, Karen Christie, J. Park, Gail Binkley, Maria C. Costanzo, Selina S. Dwight, Stacia R. Engel, D. G. Fisk, Jodi Hirschman, B. C. Hitz, C. J. Krieger, Michael Livstone, Stuart R. Miyasato, Robert S Nash, Rose Oughtred, Marek S. Skrzypek, Shuai Weng, Edith D. Wong, Kevin Zhu, Kara Dolinski, David Botstein, J. Michael Cherry   +23 more
openalex   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source