Results 11 to 20 of about 758,578 (355)

Gene Polymorphisms in Chronic Periodontitis [PDF]

International Journal of Dentistry, 2010
We aimed to conduct a review of the literature for gene polymorphisms associated with chronic periodontitis (CP) susceptibility. A comprehensive search of the literature in English was performed using the keywords: periodontitis, periodontal disease, combined with the words genes, mutation, or polymorphism.
Laine, M.L., Loos, B.G., Crielaard, W.
openaire   +6 more sources

LOXL1 gene polymorphisms are associated with exfoliation syndrome/exfoliation glaucoma risk: An updated meta-analysis.

PLoS ONE, 2021
BackgroundSingle nucleotide polymorphisms (SNPs) in the gene encoding LOXL1 are risk factors for exfoliation syndrome and exfoliation glaucoma. This meta-analysis comprehensively investigated the association between LOXL1 gene polymorphisms (rs1048661 ...
Xiaoyan Li, Jie He, Jian Sun
doaj   +1 more source

Insulin gene polymorphisms in type I diabetes, Addison's disease and the polyglandular autoimmune syndrome type II [PDF]

, 2008
Background: Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from ß-cell ...
Badenhoop, Klaus, Hahner, Stefanie, Kahles, Heinrich, Lange, Britta Kristina, Meyer, Gesine, Penna Martinez, Marissa, Ramos-Lopez, Elizabeth, Reisch, Nicole, Seissler, Jürgen, Willenberg, Holger S.   +9 more
core   +2 more sources

Unifying candidate gene and GWAS Approaches in Asthma. [PDF]

, 2010
The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS ...
Berg, Andrea von, Bufe, Albrecht, Depner, Martin, Frischer, Thomas, Genuneit, Jon, Gut, Ivo G., Heinzmann, Andrea, Illig, Thomas, Kabesch, Michael, Klopp, Norman, Kumar, Ashish, Lathrop, Mark, Laub, Otto, Liang, Liming, Michel, Sven, Mutius, Erika von, Rietschel, Ernst, Ruether, Andreas, Schedel, Michaela, Schreiber, Stefan, Simma, Burkhard, Vogelberg, Christian   +21 more
core   +9 more sources

Screening of the transcriptional regulatory regions of vascular endothelial growth factor receptor 2 (VEGFR2) in amyotrophic lateral sclerosis [PDF]

, 2007
Background Vascular endothelial growth factor (VEGF) has neurotrophic activity which is mediated by its main agonist receptor, VEGFR2. Dysregulation of VEGF causes motor neurone degeneration in a mouse model of amyotrophic lateral sclerosis (ALS), and
Brockington, A., Hartley, J., Nixon, H., Shaw, P.J., Wokke, B.   +4 more
core   +3 more sources

THE ASSOCIATION OF THE POLYMORPHISM AND GENE EXPRESSION OF HEAT SHOCK PROTEIN HSP70 GENE IN WINTER AND SUMMER IN THE SEMEN OF HOLSTEIN BULLS BORN IN IRAQ [PDF]

Basrah Journal of Veterinary Research, 2018
The HSP70 protein considered as a molecular markers to resist various stressconditions, especially high temperatures. Therefore, the high level of gene expressionof hsp70 gene is one of the ways to resist stress conditions, which can vary dependingon the
Hassan Nima Habib, Bassam Yasein Khudaier, Amad Falah Hassan, Wessam M M Saleh   +3 more
doaj   +1 more source

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
McCarty, Catherine A., Patchett, Richard, Sidjanin, Duska J., Smith, Edward M., Wilke, Russell A.   +4 more
core   +1 more source

GENE POLYMORPHISM;

The Professional Medical Journal, 2019
Introduction: Reduced bone density in postmenopausal women is a complex disease with a strong genetic association. Causative factors are both acquired and genetic. Single nucleotide polymorphisms may be associated with genetic predisposition of this condition. Objectives: The purpose of this study is to find out an association between single nucleotide
Amal Shoukat, Farwa Naqvi, Imran Aftab, Amna Mubeen, Bilal Habib, Shoaib Ahmed   +5 more
openaire   +2 more sources

Gene polymorphism and dyslipidemias

Pediatric Endocrinology Diabetes and Metabolism, 2015
Dyslipidemie to szerokie spektrum zaburzen, charakteryzujące sie nieprawidlowym stezeniem i/lub skladem lipoprotein w surowicy krwi. Objawy te mogą towarzyszyc wtornie innym chorobom, ale najcześciej mamy do czynienia z dyslipidemiami pierwotnymi, bedącymi wynikiem interakcji czynnikow środowiskowych oraz predyspozycji genetycznych.
Magdalena, Czajka, Patrycja, Rachubik, Justyna, Rzeszutek, Magdalena, Matysiak, Marcin, Kruszewski, Lucyna, Kapka-Skrzypczak   +5 more
openaire   +2 more sources

Development of a molecular method for the rapid screening and identification of the three functionally relevant polymorphisms in the human TAS2R38 receptor gene in studies of sensitivity to the bitter taste of PROP [PDF]

, 2015
The objective of this work was to develop a rapid screening method to identify the three single nucleotide polymorphisms (SNPs) in the TAS2R38 gene, with the aim of providing a significant contribution to studies designed to assess sensitivity to the ...
Atzori, E, Orrù, R, Padiglia, A
core   +2 more sources