Results 21 to 30 of about 3,153,117 (306)

IRF5 gene polymorphisms in melanoma [PDF]

Journal of Translational Medicine, 2012
Interferon regulatory factor (IRF)-5 is a transcription factor involved in type I interferon signaling whose germ line variants have been associated with autoimmune pathogenesis. Since relationships have been observed between development of autoimmunity and responsiveness of melanoma to several types of immunotherapy, we tested whether polymorphisms of
Uccellini Lorenzo, De Giorgi Valeria, Zhao Yingdong, Tumaini Barbara, Erdenebileg Narnygerel, Dudley Mark E, Tomei Sara, Bedognetti Davide, Ascierto Maria, Liu Qiuzhen, Simon Richard, Kottyan Leah, Kaufman Kenneth M, Harley John B, Wang Ena, Rosenberg Steven A, Marincola Francesco M   +16 more
openaire   +3 more sources

Gene Polymorphisms in Chronic Periodontitis [PDF]

International Journal of Dentistry, 2010
We aimed to conduct a review of the literature for gene polymorphisms associated with chronic periodontitis (CP) susceptibility. A comprehensive search of the literature in English was performed using the keywords: periodontitis, periodontal disease, combined with the words genes, mutation, or polymorphism.
Laine, M.L., Loos, B.G., Crielaard, W.
openaire   +5 more sources

A Study of Single Nucleotide Polymorphisms of Tumour Necrosis Factor α-1031 And Tumour Necrosis Factor β+ 252 in Chronic Rhinosinusitis [PDF]

Clinical and Experimental Otorhinolaryngology, 2017
Objectives This case-controlled study aimed to identify the association of tumor necrosis factor (TNF)α-1031 and TNFβ+ 252 gene polymorphisms between chronic rhinosinusitis (CRS) and healthy controls.
Khairunnisak Misron, Suzina Sheikh Ab Hamid, Azlina Ahmad, Ramiza Ramza Ramli   +3 more
doaj   +1 more source

Polymorphisms in the bradykinin B2 receptor gene and childhood asthma [PDF]

, 2001
Bradykinin has been suggested as one of the key mediators of bronchial asthma. Polymorphisms with a potential functional relevance have been described in the B2 bradykinin receptor gene.
Illi, S., Praun, M., Kusser, B., Braun, A., Mutius, Erika von, Roscher, A. A., E. von Mutius, A.A. Roscher, M. Praun, A. Braun, S. Illi, B. Kusser   +11 more
core   +2 more sources

LOXL1 gene polymorphisms are associated with exfoliation syndrome/exfoliation glaucoma risk: An updated meta-analysis.

PLoS ONE, 2021
BackgroundSingle nucleotide polymorphisms (SNPs) in the gene encoding LOXL1 are risk factors for exfoliation syndrome and exfoliation glaucoma. This meta-analysis comprehensively investigated the association between LOXL1 gene polymorphisms (rs1048661 ...
Xiaoyan Li, Jie He, Jian Sun
doaj   +1 more source

Association between TAS2R38 gene polymorphisms and colorectal cancer risk [PDF]

, 2011
Molecular sensing in the lingual mucosa and in the gastro-intestinal tract play a role in the detection of ingested harmful drugs and toxins. Therefore, genetic polymorphisms affecting the capability of initiating these responses may be critical for the ...
Stemmler, Susanne, Novotny, Jan, Steinke, Verena, Vodicka, Pavel, Morak, Monika, Hemminki, Kari, Pardini, Barbara, Engel, Christoph, Canzian, Federico, Schackert, Hans K., Naccarati, Alessio, Vodickova, Ludmila, Görgens, Heike, Propping, Peter, Barale, Roberto, Büttner, Reinhard, Försti, Asta, Carrai, Maura, Betz, Beate, Holinski-Feder, Elke, Stein, Angelika, Kloor, Matthias, Rahner, Nils, Campa, Daniele   +23 more
core   +1 more source

Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis [PDF]

, 2005
The MDR1 gene encodes P-glycoprotein 170, an efflux transporter that is highly expressed in intestinal epithelial cells. The MDR1 exonic single nucleotide polymorphisms (SNPs) C3435T and G2677T have been shown to correlate with activity/expression of P ...
Mowat, Craig, Tenesa, Albert, Arnott, Ian D, Mowat, Craig; id_orcid, Satsangi, Jack, Nimmo, Elaine R, Fennell, Janice, Nimmo, Elaine R., Arnott, Ian D., Ho, Gwo-Tzer, Drummond, Hazel   +10 more
core   +1 more source

Unifying candidate gene and GWAS Approaches in Asthma. [PDF]

, 2010
The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS ...
Heinzmann, Andrea, Ruether, Andreas, Otto Laub, Bufe, A., Lathrop, M, Schedel, M., Michel, Sven, Ruether, A., Michel, S., Schreiber, Stefan, von Berg, A., Gut, I.G., Christian Vogelberg, Ernst Rietschel, von Mutius, E., Burkhard Simma, Schreiber, S., Klopp, N., Schedel, Michaela, Depner, Martin, Laub, O., Liang, Liming, Stefan Schreiber, Illig, T., Rietschel, E., Michael Kabesch, Gut, Ivo Glynne, Mutius, Erika von, Frischer, T., Kabesch, Michael, Kabesch, M., Lathrop, Mark, Frischer, Thomas, Ashish Kumar, Jon Genuneit, Gut, Ivo G., Albrecht Bufe, Mark Lathrop, Kumar, A., Rietschel, Ernst, Ivo G. Gut, Illig, Thomas, Martin Depner, Liming Liang, Heinzmann, A., Andrea von Berg, Laub, Otto, Thomas Illig, Andreas Ruether, Simma, B., Vogelberg, Christian, Bufe, Albrecht, Erika von Mutius, Simma, Burkhard, Ivo G Gut, Kumar, Ashish, Sven Michel, Liang, L.M., Depner, M., Berg, Andrea von, Thomas Frischer, Michaela Schedel, Genuneit, J., Genuneit, Jon, Vogelberg, C., Norman Klopp, Klopp, Norman, Andrea Heinzmann, Liang Liming, Schedel Michaela, Schreiber Stefan, Ruether Andreas, Depner Martin, Kabesch Michael, Simma Burkhard, Gut Ivo G., Illig Thomas, von Berg Andrea, Kumar Ashish, Frischer Thomas, Laub Otto, Rietschel Ernst, Heinzmann Andrea, Klopp Norman, Michel Sven, Bufe Albrecht, von Mutius Erika, Genuneit Jon, Lathrop Mark, Vogelberg Christian   +89 more
core   +2 more sources

Gene polymorphism and dyslipidemias

Pediatric Endocrinology Diabetes and Metabolism, 2015
Dyslipidemie to szerokie spektrum zaburzen, charakteryzujące sie nieprawidlowym stezeniem i/lub skladem lipoprotein w surowicy krwi. Objawy te mogą towarzyszyc wtornie innym chorobom, ale najcześciej mamy do czynienia z dyslipidemiami pierwotnymi, bedącymi wynikiem interakcji czynnikow środowiskowych oraz predyspozycji genetycznych.
Magdalena, Czajka, Patrycja, Rachubik, Justyna, Rzeszutek, Magdalena, Matysiak, Marcin, Kruszewski, Lucyna, Kapka-Skrzypczak   +5 more
openaire   +2 more sources

Impact of Gene-Gender Effects of Adrenergic Polymorphisms on Hypothalamic-Pituitary-Adrenal Axis Activity in Depressed Patients [PDF]

, 2008
Objective: There is overwhelming evidence that activation of the hypothalamic-pituitary-adrenal (HPA) system plays a major role in depression and cardiovascular disease in genetically susceptible individuals.
Bondy, Brigitta, Baghai, Thomas C., Spraul, M., Zill, P., Rupprecht, R., Eser, D., Schule, C., Haefner, S.   +7 more
core   +1 more source