Results 31 to 40 of about 3,153,117 (306)

Endothelin-1 gene and endothelin receptor A gene polymorphisms in severe pulmonary hypertension associated with rheumatic mitral valve disease

open access: yes, 2022
INTRODUCTION: Endothelin-1 (ET-1) gene polymorphisms are implicated in pathogenesis of idiopathic pulmonary arterial hypertension. METHODS: We studied ET-1 (Lys198Asn and 3A/4A) and endothelin receptor A (ET) gene (His323His) polymorphisms in 123 ...
Aronow, Wilbert S   +10 more
core   +1 more source

Effects of interacting networks of cardiovascular risk genes on the risk of type 2 diabetes mellitus (the CODAM study) [PDF]

open access: yes, 2008
Background: Genetic dissection of complex diseases requires innovative approaches for identification of disease-predisposing genes. A well-known example of a human complex disease with a strong genetic component is Type 2 Diabetes Mellitus (T2DM ...
Paul MH Schiffers   +23 more
core   +2 more sources

THE ASSOCIATION OF THE POLYMORPHISM AND GENE EXPRESSION OF HEAT SHOCK PROTEIN HSP70 GENE IN WINTER AND SUMMER IN THE SEMEN OF HOLSTEIN BULLS BORN IN IRAQ [PDF]

open access: yesBasrah Journal of Veterinary Research, 2018
The HSP70 protein considered as a molecular markers to resist various stressconditions, especially high temperatures. Therefore, the high level of gene expressionof hsp70 gene is one of the ways to resist stress conditions, which can vary dependingon the
Hassan Nima Habib   +3 more
doaj   +1 more source

The analyses of C677T and A1298C Polymorphisms on the MTHFR gene and Factor V Leiden mutation in Pseudotumor Cerebri Patients [PDF]

open access: yes, 2013
Background: In this study, we aimed to investigate the genetic factors which may cause to thrombosis such as C677T and A1298C methylen-thetrahydropholate reductase (MTHFR) gene polymorphisms and Factor V Leiden mutation. Methods: A case-control study was
Aslan, Adem   +6 more
core   +4 more sources

Interleukin-1[Alpha] production in periodontal disease: the interaction of bacteria and gene polymorphisms. [PDF]

open access: yes, 2007
PhDThere is good evidence that interleukin-I alpha (IL-Ia) plays a key role in both the host response to bacteria and the tissue destruction associated with periodontal disease.
Bostanci, Nagihan
core   +2 more sources

Genetic variability of the prion protein gene (PRNP) in wild ruminants from Italy and Scotland [PDF]

open access: yes, 2009
The genetics of the prion protein gene (PRNP) play a crucial role in determining the relative susceptibility to transmissible spongiform encephalopathies (TSEs) in several mammalian species.
Acutis, Pier Luigi   +50 more
core   +1 more source

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. [PDF]

open access: yes, 2014
Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P.
Sibley, CH   +144 more
core   +2 more sources

Toll-like receptor–4 gene polymorphisms in Javanese aggressive and chronic periodontitis patients

open access: yesDental Journal, 2015
Background: Tool-like receptor-4 (TLR4) gene polymorphisms affect the ability of the host in response to pathogenic bacteria, and can also be associated with the severity of periodontitis.
Chiquita Prahasanti
doaj   +1 more source

CHD7 gene polymorphisms in female patients with idiopathic scoliosis

open access: yesBMC Musculoskeletal Disorders, 2020
Background The CHD7 (chromosome domain helicase DNA binding protein 7) gene has been associated with familial idiopathic scoliosis (IS) in families of European descent.
Karolina Borysiak   +6 more
doaj   +1 more source

Prevalence of AGER gene polymorphism in post menopause Iraqi sample with Osteoporosis and osteopenia in type 2DM

open access: yesIraqi Journal of Pharmaceutical Sciences, 2022
Osteoporosis (OP)is one of the most important metabolic disorder also affected by interaction of genetic and environmental factors by almost 70% and 30% respectively.
Murooj G Jameel   +2 more
doaj   +1 more source

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