Results 31 to 40 of about 7,390,551 (401)

Toll-like receptor–4 gene polymorphisms in Javanese aggressive and chronic periodontitis patients

open access: yesDental Journal, 2015
Background: Tool-like receptor-4 (TLR4) gene polymorphisms affect the ability of the host in response to pathogenic bacteria, and can also be associated with the severity of periodontitis.
Chiquita Prahasanti
doaj   +1 more source

TNF-α gene polymorphisms and expression

open access: yesSpringerPlus, 2016
Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine with an important role in the pathogenesis of several diseases. Its encoding gene is located in the short arm of chromosome 6 in the major histocompatibility complex class III region. Most
R. El-Tahan, A. Ghoneim, N. El-Mashad
semanticscholar   +1 more source

DVWA gene polymorphisms and osteoarthritis

open access: yesBMC Research Notes, 2015
Osteoarthritis (OA) is a degenerative joints disorder influenced by genetic predisposition. We reported that rs11718863 DVWA SNP was represented in Sicilian with a more severe Kellgren and Lawrence (KL) radiographic grade, displaying its predictive role as OA marker progression.
Valentina Bravatà 1*   +12 more
openaire   +5 more sources

CHD7 gene polymorphisms in female patients with idiopathic scoliosis

open access: yesBMC Musculoskeletal Disorders, 2020
Background The CHD7 (chromosome domain helicase DNA binding protein 7) gene has been associated with familial idiopathic scoliosis (IS) in families of European descent.
Karolina Borysiak   +6 more
doaj   +1 more source

Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals [PDF]

open access: yes, 2017
In recent years, great progress has been made in the field of new therapeutic options for hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a great hope for millions of chronically infected individuals because ...
Caputo, Mariela   +4 more
core   +1 more source

Gene Polymorphisms in Gingivitis [PDF]

open access: yes, 2011
1) We aimed to conduct a review of the literature for gene polymorphisms associated with susceptibility to gingivitis. We searched the studies in English language using the key words gingivitis and gene (mutation or polymorphism) and analyzed their results. (a) Firstly, in introduction, etiopathogenesis and clinical picture of gingivitis were discussed,
Lubomír Kukla   +6 more
openaire   +3 more sources

PTPN22 gene polymorphism in Takayasu's arteritis [PDF]

open access: yesRheumatology, 2008
Takayasu's arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase ...
Oezer, H.   +18 more
openaire   +10 more sources

Association of Rho-kinase Gene Polymorphisms with Respiratory Distress Syndrome in Preterm Neonates

open access: yesPediatrics and Neonatology, 2017
Respiratory distress syndrome (RDS) of the newborn is one of the most common causes of morbidity and mortality in preterm infants. Our objective was to determine the association between Rho-kinase (ROCK1 and ROCK2) gene polymorphisms and RDS in preterm ...
Gül Kaya   +6 more
doaj   +1 more source

A preliminary study: MUC5B promoter polymorphism and its association with IPF

open access: yesThe Egyptian Journal of Bronchology, 2020
Background The (T) allele of MUC5B gene is strongly correlated with idiopathic pulmonary fibrosis (IPF) and interstitial lung diseases (ILD) related to autoimmune conditions in Caucasians, but no data is available regarding this polymorphism in the ...
Hoda Ali Abu Yusuf   +5 more
doaj   +1 more source

Associations between IL-1RN variable number of tandem repeat, IL-1β (−511) and IL-1β (+3954) gene polymorphisms and urolithiasis in Uighur children of China

open access: yesAsian Journal of Urology, 2022
Objective: Interleukin-1 (IL-1) is a pro-inflammatory cytokine which may be related to urolithiasis. Genetic polymorphisms of the interleukin-1beta (IL-1β) have been proposed as markers for urolithiasis in some areas.
Jiefeng Xiao   +3 more
doaj   +1 more source

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