Results 121 to 130 of about 859,450 (301)

Traces of Human-Mediated Selection in the Gene Pool of Red Deer Populations. [PDF]

Animals (Basel), 2023
Moravčíková N, Kasarda R, Židek R, McEwan JC, Brauning R, Landete-Castillejos T, Chonco L, Ciberej J, Pokorádi J.   +8 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

MOBILIZATION AND CONSERVATION OF THE SEED POOL OF PLANT GENETIC RESOURCES IN AZERBAIJAN

Вавиловский журнал генетики и селекции, 2014
The article is dedicated to fund-raising activities and the conservation of plant genetic resources in Azerbaijan. Brief information is provided on the activities of the National Gene Bank, functioning at the Institute of Genetics Resources of the ...
Z. I. Akparov, S. A. Mammadova, A. T. Mammadov   +2 more
doaj  

Exploring functional InDels and genetic diversity: agro-morphometric and molecular insights into the Western and Eastern gene pools of carrot (Daucus carota L.)

Frontiers in Plant Science
Carrot (Daucus carota L.) is a globally cultivated root vegetable with significant genetic diversity. This first study generated and validated carrot InDels to unravel the genetic divergence between Eastern and Western gene pools, integrating agro ...
Trupthi Mudihal, Sarvamangala Cholin, Chaitra C. Kulkarni, K. M. Shivaprasad, Prakash Kumar, William Rolling, Philipp Simon, Philipp Simon   +7 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Genetic divergence and population structure analysis of common bean accessions from Garhwal Himalayas

Spanish Journal of Agricultural Research
Aim of study: Collection of common bean accessions from different villages of Garhwal Himalayan region and assessment of their genetic diversity. Area of study: Field trials were conducted at New Tehri, Tehri Garhwal, Uttarakhand.
Navneeti Chamoli, Deepti Prabha, Jai S. Chauhan   +2 more
doaj   +1 more source

Effect Size Estimation and Misclassification Rate Based Variable Selection in Linear Discriminant Analysis [PDF]

, 2012
Supervised classifying of biological samples based on genetic information, (e.g. gene expression profiles) is an important problem in biostatistics. In order to find both accurate and interpretable classification rules variable selection is indispensable.
Klaus, Bernd
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Discovering useful genetic variation in the seed parent gene pool for sorghum improvement. [PDF]

Front Genet, 2023
Kumar N, Boatwright JL, Sapkota S, Brenton ZW, Ballén-Taborda C, Myers MT, Cox WA, Jordan KE, Kresovich S, Boyles RE.   +9 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source