Results 111 to 120 of about 3,252,139 (303)

Exploring functional InDels and genetic diversity: agro-morphometric and molecular insights into the Western and Eastern gene pools of carrot (Daucus carota L.)

open access: yesFrontiers in Plant Science
Carrot (Daucus carota L.) is a globally cultivated root vegetable with significant genetic diversity. This first study generated and validated carrot InDels to unravel the genetic divergence between Eastern and Western gene pools, integrating agro ...
Trupthi Mudihal   +7 more
doaj   +1 more source

Traces of Human-Mediated Selection in the Gene Pool of Red Deer Populations. [PDF]

open access: yesAnimals (Basel), 2023
Moravčíková N   +8 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Genetic divergence and population structure analysis of common bean accessions from Garhwal Himalayas

open access: yesSpanish Journal of Agricultural Research
Aim of study: Collection of common bean accessions from different villages of Garhwal Himalayan region and assessment of their genetic diversity. Area of study: Field trials were conducted at New Tehri, Tehri Garhwal, Uttarakhand.
Navneeti Chamoli   +2 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Microglial efferocytosis: Diving into the Alzheimer's disease gene pool. [PDF]

open access: yesNeuron, 2022
Romero-Molina C   +4 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

[News Clip: Pool]

open access: yes, 1958
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about the dedication of Como pool in Fort Worth, a segregated, blacks-only ...
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

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