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The Pool of Harmful Genes in Human Populations
Acta geneticae medicae et gemellologiae, 1962The concepts of dominance and recessivity as applied to human genetical traits are losing their original connotations. It is better to speak of genes unconditionally deleterious in heterozygote form and those for which such disadvantage is doubtful. The classical dominant traits come into the first category and in the large majority they give rise to ...
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The diverse origins of the human gene pool
Nature Reviews Genetics, 2015Analyses of the genomes of Neanderthals and Denisovans, the closest evolutionary relatives of present-day humans, suggest that our ancestors were part of a web of now-extinct populations linked by limited, but intermittent or sometimes perhaps even persistent, gene flow.
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Psoriasis, innate immunity, and gene pools
Journal of the American Academy of Dermatology, 2007Recently, emphasis has shifted from T cells to innate (natural) immunity as the possible major culprit in psoriasis. All known elements of innate immune responses are up-regulated in psoriasis lesions, which must have a polygenetic origin. We hypothesize that urbanized populations have been under evolutionary pressure that selects for increased innate ...
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[Gene pool and gene geography of the USSR population].
Genetika, 1992Gene pool and gene geography are discussed from the point of view of their conceptual history beginning from the original concept of A.S. Serebrovskiĭ (1928). Difference between the present-day gene geography and gene geography of gene pool is accentuated: the former only represents a portion of the latter.
Iu G, Rychkov, E V, Balanovskaia
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The integrity of the human gene pool
Environmental and Molecular Mutagenesis, 1996openaire +2 more sources