Results 31 to 40 of about 3,252,139 (303)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Diversity analysis, nutrition, and flavor evaluation of amino acids in Chinese native geese germplasms [PDF]
Background and Aim: As living standards improve and consumption patterns shift, the market for goose meat continues to grow because of its exceptional dietary quality and distinctive flavor.
Haiyue Cao +14 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
To investigate the genetic factors underlying marketed body size traits in Chinese local geese, we conducted a comprehensive study involving nine body size traits in 251 samples at 10 weeks of age from five local breeds: Taihu goose (TH), Sichuan goose ...
Guobo Sun +21 more
doaj +1 more source
Objective: This study aimed to measure the anthelmintic effects of betel nut (Areca catechu) and neem (Azadirachta indica) leaf extracts against Fasciola spp.
Elnalyn C. Yamson +3 more
doaj +1 more source
Conservation status of white poplar (Populus alba L.) and black poplar (Populus nigra L.) in the territory of Great War Island [PDF]
T he paper describes t he conservation status of white poplar (Populus alba L.) and black poplar (Populus nigra L.) in the territory of Great War Island.
Šijačić-Nikolić Mirjana +4 more
doaj +1 more source
Understanding pool-riffle dynamics through continuous morphological simulations
Pool-riffle dynamics is governed by complex time and spatial interactions between water and sediment flows. In the last few decades, significant advances have been made in characterizing and modeling the hydrodynamics of pool-riffle sequences, and this ...
José F. Rodríguez +5 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

