Results 191 to 200 of about 168,249 (259)

Tick-borne bacterial pathogens in wildlife and their parasitizing ticks in Korea: A molecular epidemiological study. [PDF]

Parasites Hosts Dis
Lee YJ, Kim B, Hyun YS, Heo JW, Woo HM, Choi JW, Choi I, Kang YM, Rhee MH, Kwak D, Kim KT, Seo MG.   +11 more
europepmc   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

A high-throughput co-culture CRISPR array for rapid fitness hypothesis testing and growth engineering in CHO cells. [PDF]

iScience
Marzluf JP, Huckfeldt L, Haidas D, Zehe C, Leroux AC.   +4 more
europepmc   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Automated zonal-rotor CsCl ultracentrifugation with ÄKTA-based fractionation removes empty and intermediate AAV capsids. [PDF]

Mol Ther Adv
Horita K, Miyauchi R, Yamamoto H, Yamazaki Y, Nagatomo K, Aburatani T, Takeda S, Baba S.   +7 more
europepmc   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

A case of misleading conclusion: a critical reassessment of methodological and interpretive flaws of a recent meta-analysis on the vector role of cat fleas in feline hemotropic Mycoplasma species. [PDF]

Parasit Vectors
Moore CO, Lashnits E, Lappin M, Breitschwerdt EB.   +3 more
europepmc   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

Advanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag, Janina A. Hoffmann, Tim Rogers, Christian A. Yates   +3 more
wiley   +1 more source

Evidence of dengue transmission and a diverse Aedes mosquito virome on the Congo's Angola border. [PDF]

Nat Commun
He W, Bobanga T, Piantadosi A, Popkin-Hall ZR, Vulu F, Collins MH, Kashamuka MM, Tshefu AK, Juliano JJ, Parr JB.   +9 more
europepmc   +1 more source

Responses of Soil Carbon and Nitrogen Cycling Gene Abundances to Winter Green Manure Incorporation in a Ratoon Rice System. [PDF]

Plants (Basel)
Shao P, Chen S, Jia S, Shi M, Hou Q, Yang Z, Zhong L, Yuan Z, Huang C, Fu Z, Long P, Xu Y.   +11 more
europepmc   +1 more source