Results 201 to 210 of about 319,651 (293)

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

Evaluation of gene editing in CHO cells using the Cas-CLOVER system. [PDF]

Biotechnol Prog
McLamarrah T, Aral E, Hoffman M, Tedstone J, King T, Vitko J, Sebastião MJ, Escandell JM, Dias MM, McCall I, Machado D, Cairns V, DeMaria C, Scarcelli JJ.   +13 more
europepmc   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

The regulation, function and disease relevance of cytoplasmic tRNAs. [PDF]

Nat Rev Mol Cell Biol
Stanley RE, Lowe TM, Ignatova Z.
europepmc   +1 more source

Taming the wild: resolving the gene pools of non-model Arabidopsis lineages. [PDF]

BMC Evol Biol, 2014
Hohmann N, Schmickl R, Chiang TY, Lučanová M, Kolář F, Marhold K, Koch MA.   +6 more
europepmc   +1 more source

Editorial: Expanding the Gene Pool

Complicity: An International Journal of Complexity and Education, 2014
openaire   +2 more sources

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

A Pooled Blood Genome-Wide Association Study of Hypertension in Sindhi Families: Results from the DISFIN Study. [PDF]

Genes (Basel)
Kanaskar S, Patel AA, Jaisinghani MT, Pipal KV, Kanaskar M, Mamtani M, Kulkarni H.   +6 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Detection of novel <i>Wolbachia</i> strains in <i>Aedes aegypti</i> populations from a recent arbovirus outbreak region in Pune District, Maharashtra, India (2024). [PDF]

Front Microbiol
Hari I, Panner Selvam TP, Ray SK, Kalichamy A, Sharma V, Thiruvengadam K, Lole KS, Ramdasi A, Hundekar S, Ayachit PV, Gaikwad P, Rathinam B, Anuse SS, Baruah K.   +13 more
europepmc   +1 more source