Results 121 to 130 of about 563,010 (309)

Prediction of a Gene Regulatory Network from Gene Expression Profiles With Linear Regression and Pearson Correlation Coefficient [PDF]

, 2018
Mehedi Hassan Onik, Shakhawat Ahmmed Nobin, Adnan Ferdous Ashrafi, Tareque Mohmud Chowdhury   +3 more
openalex   +1 more source

Genetic Mapping and Candidate Gene Prediction of a QTL Related to Early Heading on Wild Emmer Chromosome 7BS in the Genetic Background of Common Wheat [PDF]

, 2022
Fei Lu, Manxia Chen, Yanhao Zhao, Shaoxin Wu, Muhammad Yasir, Hua Zhang, Xin Hu, Junkang Rong   +7 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Integration of summary data from GWAS and eQTL studies identified novel causal BMD genes with functional predictions

, 2018
Xiang-He Meng, Xiang‐Ding Chen, Jonathan Greenbaum, Qin Zeng, Sheng-Lan You, Hong‐Mei Xiao, Lijun Tan, Hong‐Wen Deng   +7 more
openalex   +2 more sources

uspA gene-based phylogenetic analysis and antigenic epitope prediction for Escherichia coli strains of avian origin [PDF]

, 2023
Kushal Grakh, Dinesh Mittal, Anand Prakash, Ramesh Kumar, Naresh Jindal   +4 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

HGPEC: a Cytoscape app for prediction of novel disease-gene and disease-disease associations and evidence collection based on a random walk on heterogeneous network

, 2017
Duc‐Hau Le
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

FESNov gene families protein structure predictions

, 2023
Álvaro Rodríguez del Río, Joaquín Giner‐Lamia, Carlos P. Cantalapiedra, Jorge Botas, Ziqi Deng, Ana Hernández-Plaza, Munar-Palmer Marti, Saray Santamaría‐Hernando, José J. Rodríguez‐Herva, Hans‐Joachim Ruscheweyh, Lucas Paoli, Thomas Schmidt, Sinichi Sunagawa, Peer Bork, López-Solanilla Emilia, Luís Pedro Coelho, Jaime Huerta‐Cepas   +16 more
openalex   +1 more source

CRISPRedict: The case for simple and interpretable efficiency prediction for CRISPR-Cas9 gene editing [PDF]

, 2022
Vasileios Konstantakos, Anastasios Nentidis, Anastasia Krithara, Γεώργιος Παλιούρας   +3 more
openalex   +1 more source