Results 181 to 190 of about 563,010 (309)

Gene prediction of aging-related diseases based on DNN and Mashup. [PDF]

open access: yesBMC Bioinformatics, 2021
Ye J, Wang S, Yang X, Tang X.
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Altered expression spectrum and target gene prediction of tRNA-derived small RNAs in clear cell renal cell carcinoma. [PDF]

open access: yesBMC Cancer
Liu S   +15 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Leveraging Transcriptomics-Based Approaches to Enhance Genomic Prediction: Integrating SNP weights and gene-networks for Cotton Fibre Quality Improvement [PDF]

open access: gold
Nima Khalili Samani   +5 more
openalex   +1 more source

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