Results 11 to 20 of about 9,911,867 (381)
A benchmark study of ab initio gene prediction methods in diverse eukaryotic organisms
BMC Genomics, 2020 Background The draft genome assemblies produced by new sequencing technologies present important challenges for automatic gene prediction pipelines, leading to less accurate gene models.
Nicolas Scalzitti +4 more
doaj +2 more sources
Combining RNA-seq data and homology-based gene prediction for plants, animals and fungi
BMC Bioinformatics, 2018 Background Genome annotation is of key importance in many research questions. The identification of protein-coding genes is often based on transcriptome sequencing data, ab-initio or homology-based prediction.
Jens Keilwagen +4 more
doaj +2 more sources
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function [PDF]
Nucleic Acids Research, 2010 GeneMANIA (http://www.genemania.org) is a flexible, user-friendly web interface for generating hypotheses about gene function, analyzing gene lists and prioritizing genes for functional assays.
David Warde-Farley +16 more
semanticscholar +3 more sources
AGenDA: homology-based gene prediction [PDF]
Bioinformatics, 2003 Abstract Summary: We present a www server for homology-based gene prediction. The user enters a pair of evolutionary related genomic sequences, for example from human and mouse. Our software system uses CHAOS and DIALIGN to calculate an alignment of the input sequences and then searches for conserved splicing signals and start/stop ...
Leila Taher +6 more
openalex +7 more sources
Study of integrated heterogeneous data reveals prognostic power of gene expression for breast cancer survival. [PDF]
PLoS ONE, 2015 BackgroundStudies show that thousands of genes are associated with prognosis of breast cancer. Towards utilizing available genetic data, efforts have been made to predict outcomes using gene expression data, and a number of commercial products have been ...
Richard E Neapolitan, Xia Jiang
doaj +5 more sources
Genome Assemblies of Two Ormosia Species: Gene Duplication Related to Their Evolutionary Adaptation
Agronomy, 2023 Ormosia is a genus of the Fabaceae family that shows a distinct evolutionary history due to its typical Asian-American tropical disjunction distribution pattern. However, both its phylogeny and biogeographic mechanisms have not been fully resolved.
Pan-Pan Liu +6 more
doaj +1 more source
Recent Advances in Network-based Methods for Disease Gene Prediction [PDF]
Briefings Bioinform., 2020 Disease-gene association through genome-wide association study (GWAS) is an arduous task for researchers. Investigating single nucleotide polymorphisms that correlate with specific diseases needs statistical analysis of associations. Considering the huge
S. Ata +5 more
semanticscholar +1 more source
Journal of Open Source Software, 2022 Improvements in sequencing technologies have seen the amount of available genomic data expand considerably over the last twenty years. One of the key steps for analysing is the prediction of protein-coding regions in genomic sequences, known as Open ...
M. Larralde
semanticscholar +1 more source
Semi-Supervised Pipeline for Autonomous Annotation of SARS-CoV-2 Genomes
Viruses, 2021 SARS-CoV-2 genomic sequencing efforts have scaled dramatically to address the current global pandemic and aid public health. However, autonomous genome annotation of SARS-CoV-2 genes, proteins, and domains is not readily accomplished by existing methods ...
Kristen L. Beck +9 more
doaj +1 more source
T-Gene: improved target gene prediction [PDF]
Bioinformatics, 2019 Abstract Motivation Identifying the genes regulated by a given transcription factor (TF) (its ‘target genes’) is a key step in developing a comprehensive understanding of gene regulation. Previously, we developed a method (CisMapper) for predicting the target genes of a TF based solely on the ...
Timothy O’Connor +3 more
openaire +5 more sources