Results 21 to 30 of about 9,695,054 (384)
Frontiers in Medicine, 2022 BackgroundThe long-term health consequences of coronavirus disease 2019 (COVID-19) remain largely unclear. This study aimed to apply the Mendelian randomization (MR) design to estimate the causal associations between COVID-19 and ten cardiovascular ...
Min Jia +3 more
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SNAPper: gene order predicts gene function [PDF]
Bioinformatics, 2002 Abstract Summary: SNAPper is a network service for predicting gene function based on the conservation of gene order. Availability: The SNAPper server is available at http://pedant.gsf.de/snapper. SNAPper-based functional predictions will soon be offered as part of the PEDANT genome analysis server http://pedant.gsf.de.
Kolesov, G., Mewes, H.-W., Frishman, D.
openaire +4 more sources
Gene therapy: progress and predictions [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2015 The first clinical gene delivery, which involved insertion of a marker gene into lymphocytes from cancer patients, was published 25 years ago. In this review, we describe progress since then in gene therapy. Patients with some inherited single-gene defects can now be treated with their own bone marrow stem cells that have been engineered with a viral ...
Adrian J. Thrasher, Mary Collins
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A Gene-disease Association Prediction Algorithm Based on Multi-source Data Fusion [PDF]
International Journal Bioautomation, 2022 Accurate gene-disease association prediction results are the basis for effective diagnosis and treatment of complex genetic diseases. However, existing studies related to this topic generally face problems in two aspects: large volume of original data ...
Fei Wang
doaj +1 more source
PrismEXP: gene annotation prediction from stratified gene-gene co-expression matrices [PDF]
PeerJ, 2023 Background Gene-gene co-expression correlations measured by mRNA-sequencing (RNA-seq) can be used to predict gene annotations based on the co-variance structure within these data.
Alexander Lachmann +5 more
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AGenDA: homology-based gene prediction [PDF]
Bioinformatics, 2003 Abstract Summary: We present a www server for homology-based gene prediction. The user enters a pair of evolutionary related genomic sequences, for example from human and mouse. Our software system uses CHAOS and DIALIGN to calculate an alignment of the input sequences and then searches for conserved splicing signals and start/stop ...
Leila Taher +6 more
openalex +7 more sources
An Integrated Pipeline for Annotation and Visualization of Metagenomic Contigs
Frontiers in Genetics, 2019 Here, we describe MetaErg, a standalone and fully automated metagenome and metaproteome annotation pipeline. Annotation of metagenomes is challenging. First, metagenomes contain sequence data of many organisms from all domains of life.
Xiaoli Dong, Marc Strous
doaj +1 more source
Susceptibility Gene Prediction in Hereditary Disease Retinoblastoma [PDF]
, 2017 Nowadays Bioinformatics, proteomics and Genomics are the most intriguing sciences to understand the human genome and diseases. Several hereditary genetic diseases like Retinoblastoma involve a sequence of complex interactions between multiple biological ...
Dhaya, R. (R) +2 more
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BUSCO Applications from Quality Assessments to Gene Prediction and Phylogenomics
bioRxiv, 2017 Genomics promises comprehensive surveying of genomes and metagenomes, but rapidly changing technologies and expanding data volumes make evaluation of completeness a challenging task. Technical sequencing quality metrics can be complemented by quantifying
Robert M. Waterhouse +7 more
semanticscholar +1 more source
BMC Bioinformatics, 2020 Recent advances in sequencing technologies have led to an explosion in the number of genomes available, but accurate genome annotation remains a major challenge.
C. Meyer +5 more
semanticscholar +1 more source