Results 31 to 40 of about 9,695,054 (384)

Predicting Synthetic Gene Networks [PDF]

open access: yes, 2011
Synthetic biology aims at designing and building new biological functions in living organisms. The complexity of cellular regulation (regulatory, metabolic, and signaling interactions, and their coordinated action) can be tackled via the development of quantitative mathematical models.
di Bernardo, Diego   +3 more
openaire   +3 more sources

Machine Learning Analysis Identifies Drosophila Grunge/Atrophin as an Important Learning and Memory Gene Required for Memory Retention and Social Learning

open access: yesG3: Genes, Genomes, Genetics, 2017
High-throughput experiments are becoming increasingly common, and scientists must balance hypothesis-driven experiments with genome-wide data acquisition. We sought to predict novel genes involved in Drosophila learning and long-term memory from existing
Balint Z. Kacsoh   +2 more
doaj   +1 more source

Evolution of the Highly Repetitive PEVK Region of Titin Across Mammals

open access: yesG3: Genes, Genomes, Genetics, 2019
The protein titin plays a key role in vertebrate muscle where it acts like a giant molecular spring. Despite its importance and conservation over vertebrate evolution, a lack of high quality annotations in non-model species makes comparative evolutionary
Kathleen Muenzen   +2 more
doaj   +1 more source

Comprehensive evaluation of protein-coding sORFs prediction based on a random sequence strategy

open access: yesFrontiers in Bioscience-Landmark, 2021
Background: Small open reading frames (sORFs) with protein-coding ability present unprecedented challenge for genome annotation because of their short sequence and low expression level.
Jiafeng Yu   +8 more
doaj   +1 more source

Architecture and Distribution of Introns in Core Genes of Four Fusarium Species

open access: yesG3: Genes, Genomes, Genetics, 2017
Removal of introns from transcribed RNA represents a crucial step during the production of mRNA in eukaryotes. Available whole-genome sequences and expressed sequence tags (ESTs) have increased our knowledge of this process and revealed various ...
Mmatshepho M. Phasha   +5 more
doaj   +1 more source

In silico Gene Characterization and biological annotation of Aspergillus niger CBS 513.88 [PDF]

open access: yes, 2011
Genome annotation is the process of estimation of biological features from genomic data. The target of a genome annotation is to identify the key features of the genome sequence particularly, the genes and gene products.
Anuraj Nayarisseri   +5 more
core   +2 more sources

PlasGUN: gene prediction in plasmid metagenomic short reads using deep learning

open access: yesBioinform., 2020
Summary We present the first tool of gene prediction, PlasGUN, for plasmid metagenomic short-read data. The tool, developed based on deep learning algorithm of multiple input Convolutional Neural Network, demonstrates much better performance when tested ...
Zhencheng Fang   +6 more
semanticscholar   +1 more source

Automatic Gene Function Prediction in the 2020’s [PDF]

open access: yesGenes, 2020
The current rate at which new DNA and protein sequences are being generated is too fast to experimentally discover the functions of those sequences, emphasizing the need for accurate Automatic Function Prediction (AFP) methods. AFP has been an active and growing research field for decades and has made considerable progress in that time.
Roeland C. H. J. van Ham   +3 more
openaire   +4 more sources

Fully automated annotation of mitochondrial genomes using a cluster-based approach with de Bruijn graphs

open access: yesFrontiers in Genetics, 2023
A wide range of scientific fields, such as forensics, anthropology, medicine, and molecular evolution, benefits from the analysis of mitogenomic data. With the development of new sequencing technologies, the amount of mitochondrial sequence data to be ...
Lisa Fiedler   +2 more
doaj   +1 more source

Draft Sequencing of the Heterozygous Diploid Genome of Satsuma (Citrus unshiu Marc.) Using a Hybrid Assembly Approach

open access: yesFrontiers in Genetics, 2017
Satsuma (Citrus unshiu Marc.) is one of the most abundantly produced mandarin varieties of citrus, known for its seedless fruit production and as a breeding parent of citrus. De novo assembly of the heterozygous diploid genome of Satsuma (“Miyagawa Wase”)
Tokurou Shimizu   +8 more
doaj   +1 more source

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