Results 41 to 50 of about 9,911,867 (381)

Architecture and Distribution of Introns in Core Genes of Four Fusarium Species

open access: yesG3: Genes, Genomes, Genetics, 2017
Removal of introns from transcribed RNA represents a crucial step during the production of mRNA in eukaryotes. Available whole-genome sequences and expressed sequence tags (ESTs) have increased our knowledge of this process and revealed various ...
Mmatshepho M. Phasha   +5 more
doaj   +1 more source

MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]

open access: yes, 2012
Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Cauchi, Michael   +2 more
core   +1 more source

An Integrated Pipeline for Annotation and Visualization of Metagenomic Contigs

open access: yesFrontiers in Genetics, 2019
Here, we describe MetaErg, a standalone and fully automated metagenome and metaproteome annotation pipeline. Annotation of metagenomes is challenging. First, metagenomes contain sequence data of many organisms from all domains of life.
Xiaoli Dong, Marc Strous
doaj   +1 more source

Comprehensive evaluation of protein-coding sORFs prediction based on a random sequence strategy

open access: yesFrontiers in Bioscience-Landmark, 2021
Background: Small open reading frames (sORFs) with protein-coding ability present unprecedented challenge for genome annotation because of their short sequence and low expression level.
Jiafeng Yu   +8 more
doaj   +1 more source

Evolution of the Highly Repetitive PEVK Region of Titin Across Mammals

open access: yesG3: Genes, Genomes, Genetics, 2019
The protein titin plays a key role in vertebrate muscle where it acts like a giant molecular spring. Despite its importance and conservation over vertebrate evolution, a lack of high quality annotations in non-model species makes comparative evolutionary
Kathleen Muenzen   +2 more
doaj   +1 more source

Fully automated annotation of mitochondrial genomes using a cluster-based approach with de Bruijn graphs

open access: yesFrontiers in Genetics, 2023
A wide range of scientific fields, such as forensics, anthropology, medicine, and molecular evolution, benefits from the analysis of mitogenomic data. With the development of new sequencing technologies, the amount of mitochondrial sequence data to be ...
Lisa Fiedler   +2 more
doaj   +1 more source

PlasGUN: gene prediction in plasmid metagenomic short reads using deep learning

open access: yesBioinform., 2020
Summary We present the first tool of gene prediction, PlasGUN, for plasmid metagenomic short-read data. The tool, developed based on deep learning algorithm of multiple input Convolutional Neural Network, demonstrates much better performance when tested ...
Zhencheng Fang   +6 more
semanticscholar   +1 more source

Netter: re-ranking gene network inference predictions using structural network properties [PDF]

open access: yes, 2016
Background: Many algorithms have been developed to infer the topology of gene regulatory networks from gene expression data. These methods typically produce a ranking of links between genes with associated confidence scores, after which a certain ...
Demeester, Piet   +3 more
core   +2 more sources

Using intron position conservation for homology-based gene prediction

open access: yesNucleic Acids Research, 2016
Annotation of protein-coding genes is very important in bioinformatics and biology and has a decisive influence on many downstream analyses. Homology-based gene prediction programs allow for transferring knowledge about protein-coding genes from an ...
J. Keilwagen   +5 more
semanticscholar   +1 more source

Comparative Gene Prediction in Human and Mouse [PDF]

open access: yesGenome Research, 2003
The completion of the sequencing of the mouse genome promises to help predict human genes with greater accuracy. While current ab initio gene prediction programs are remarkably sensitive (i.e., they predict at least a fragment of most genes), their specificity is often low, predicting a large number of false-positive genes in the human genome. Sequence
Parra, Genís   +5 more
openaire   +5 more sources

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